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PROSTAGLANDIN ENDOPEROXIDE SYNTHASE [1 record]
Record 1 - internal organization data 2006-10-03
Record 1, English
Record 1, Subject field(s)
- Biochemistry
Record 1, Main entry term, English
- cyclooxygenase
1, record 1, English, cyclooxygenase
correct
Record 1, Abbreviations, English
- COX 2, record 1, English, COX
correct
Record 1, Synonyms, English
- cyclo-oxygenase 3, record 1, English, cyclo%2Doxygenase
correct
- COX 4, record 1, English, COX
correct
- COX 4, record 1, English, COX
- prostaglandin endoperoxide synthase 5, record 1, English, prostaglandin%20endoperoxide%20synthase
correct
- PTGS 6, record 1, English, PTGS
correct
- PTGS 6, record 1, English, PTGS
- prostaglandin synthetase 7, record 1, English, prostaglandin%20synthetase
correct
- prostaglandin synthase 8, record 1, English, prostaglandin%20synthase
correct
- PGS 9, record 1, English, PGS
correct
- PGS 9, record 1, English, PGS
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
An enzyme protein complex present in most tissues that catalyses two steps in prostaglandin biosynthesis and produces prostaglandins and thromboxanes from arachidonic acid. 10, record 1, English, - cyclooxygenase
Record number: 1, Textual support number: 1 CONT
Prostaglandin endoperoxide synthases (PTGS), commonly referred to as cyclooxygenases (COX-1 and COX-2), catalyze the key step in the synthesis of biologically active prostaglandins (PGs), the conversion of arachidonic acid (AA) into prostaglandin H2 (PGH2). 11, record 1, English, - cyclooxygenase
Record number: 1, Textual support number: 1 OBS
The cyclooxygenase activity is inhibited by aspirin-like drugs, accounting for their anti-inflammatory effects. 10, record 1, English, - cyclooxygenase
Record 1, French
Record 1, Domaine(s)
- Biochimie
Record 1, Main entry term, French
- cyclo-oxygénase
1, record 1, French, cyclo%2Doxyg%C3%A9nase
correct, feminine noun
Record 1, Abbreviations, French
- COX 1, record 1, French, COX
correct, feminine noun
Record 1, Synonyms, French
- cyclooxygénase 2, record 1, French, cyclooxyg%C3%A9nase
correct, feminine noun
- COX 2, record 1, French, COX
correct, feminine noun
- COX 2, record 1, French, COX
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Enzyme qui permet la formation de prostaglandines à partir de l'acide arachidonique [un acide gras qui contribue à la fabrication des parois cellulaires]. 3, record 1, French, - cyclo%2Doxyg%C3%A9nase
Record number: 1, Textual support number: 1 CONT
La cyclo-oxygénase existe sous deux isoformes : la Cox1, isoforme constitutive de la plupart des tissus et la Cox2, isoforme inductible (par les cytokines, l'endotoxine et les mitogènes). Tous les A.I.N.S. [anti-inflammatoires non stéroïdiens] actuels sont spécifiques de la Cox1 et le rôle ubiquitaire des prostaglandines dans l'organisme (coagulation, bronchomotricité, filtration rénale, contractions utérines, neurotransmission chimique) explique les indications très variées des A.I.N.S., ainsi que la richesse de leurs effets indésirables. 4, record 1, French, - cyclo%2Doxyg%C3%A9nase
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioquímica
Record 1, Main entry term, Spanish
- ciclooxigenasa
1, record 1, Spanish, ciclooxigenasa
feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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