TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
RESTRICTION MODIFICATION [1 record]
Record 1 - internal organization data 2004-10-27
Record 1, English
Record 1, Subject field(s)
- Molecular Biology
- Genetics
Record 1, Main entry term, English
- host-controlled restriction
1, record 1, English, host%2Dcontrolled%20restriction
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- host restriction 2, record 1, English, host%20restriction
correct
- restriction and modification 3, record 1, English, restriction%20and%20modification
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Bacterial defence mechanism requiring the action of methylases and restriction enzymes to protect the cell from invading DNA (such as plasmid or bacteriophage DNA). 3, record 1, English, - host%2Dcontrolled%20restriction
Record number: 1, Textual support number: 1 CONT
This phenomenon of "host-controlled restriction" was first described in the 1950s. Werner Arber, a Swiss microbiologist, subsequently advanced a molecular explanation. He suggested that bacteria cope with phages by "restriction-modification" (genetically-controlled enzymatic reactions). 1, record 1, English, - host%2Dcontrolled%20restriction
Record 1, Key term(s)
- host-controlled restriction
Record 1, French
Record 1, Domaine(s)
- Biologie moléculaire
- Génétique
Record 1, Main entry term, French
- restriction-modification
1, record 1, French, restriction%2Dmodification
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Processus qui met en jeu des enzymes de type endonucléase (enzyme de restriction) et méthylase (enzyme de modification) et qui permet à une bactérie de se défendre contre l'insertion de l'ADN d'un organisme étranger tout en protégeant son propre matériel génétique. 2, record 1, French, - restriction%2Dmodification
Record number: 1, Textual support number: 1 CONT
Si le composant antitoxine n'est pas présent (le concept inclut la restriction-modification où des nucléases spéciales attaquent les ADN qui ne sont pas protégés par une enzyme modifiant chimiquement l'ADN pour le protéger) le composant toxine estropie la cellule. 1, record 1, French, - restriction%2Dmodification
Record 1, Key term(s)
- restriction modification
Record 1, Spanish
Record 1, Textual support, Spanish
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