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RESTRICTION MODIFICATION SYSTEM [1 record]
Record 1 - internal organization data 2004-12-10
Record 1, English
Record 1, Subject field(s)
- Molecular Biology
- Genetics
Record 1, Main entry term, English
- restriction-modification system
1, record 1, English, restriction%2Dmodification%20system
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- restriction and modification system 1, record 1, English, restriction%20and%20modification%20system
correct
- host restriction system 2, record 1, English, host%20restriction%20system
correct
- host restriction-modification system 3, record 1, English, host%20restriction%2Dmodification%20system
correct
- modification-restriction system 4, record 1, English, modification%2Drestriction%20system
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 OBS
This is a system comprised of two enzymatic activities: one a restriction endonuclease that cuts DNA and the other, a methylase that modifies DNA at the same sequence. The idea being that the bacteria's own DNA is modified at the proper sites and hence is protected from the action of the restriction enzyme. However if foreign DNA enters the cell, such as by transformation or by a virus, that DNA is "foreign" and not correctly modified, hence it is a substrate for the restriction enzyme and is cut up into small pieces. 5, record 1, English, - restriction%2Dmodification%20system
Record number: 1, Textual support number: 2 OBS
This "enzyme system" if only found in prokaryotes. 6, record 1, English, - restriction%2Dmodification%20system
Record 1, Key term(s)
- restriction modification system
- host restriction modification system
Record 1, French
Record 1, Domaine(s)
- Biologie moléculaire
- Génétique
Record 1, Main entry term, French
- système de restriction-modification
1, record 1, French, syst%C3%A8me%20de%20restriction%2Dmodification
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- système enzymatique de restriction-modification 2, record 1, French, syst%C3%A8me%20enzymatique%20de%20restriction%2Dmodification
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Système de défense des bactéries contre l'infection des bactériophages qui met en jeu deux types d'enzymes, des méthylases (enzymes de modification) et des endonucléases (enzymes de restriction). 3, record 1, French, - syst%C3%A8me%20de%20restriction%2Dmodification
Record number: 1, Textual support number: 1 OBS
Lorsque l'ADN d'un phage pénètre dans une bactérie, il est susceptible de rencontrer deux enzymes, une endonucléase (ou enzyme de restriction) et une méthylase (ou enzyme de modification). La plupart du temps c'est l'endonucléase qui agit en premier et coupe l'ADN étranger, qui se trouve ainsi détruit et devient inactif. La bactérie s'est ainsi protégée de l'infection virale. 1, record 1, French, - syst%C3%A8me%20de%20restriction%2Dmodification
Record 1, Spanish
Record 1, Textual support, Spanish
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