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SEK1 [1 record]

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Record 1 1996-09-30

English

Subject field(s)
  • Biochemistry
  • Genetics
CONT

The stress-activated protein kinases (SAPKs), which are distantly related to the MAP kinases, are the dominant c-Jun amino-terminal protein kinases activated in response to a variety of cellular stresses, including treatment with tumour-necrosis factor-alpha and interleukin-beta[...] We have now identified a novel protein kinase, called SAPK/ERK kinase-1 (SEK1), which is structurally related to the MAP kinase kinases (MEKs). SEK1 is a potent activator of the SAPKs in vitro and in vivo.

OBS

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Excerpt from Nature 372, 794-8, 1994.

French

Domaine(s)
  • Biochimie
  • Génétique

Spanish

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