TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

Slowing of the rate of a chemical reaction owing to the presence of structures on the reagents that mechanically interfere with the motions associated with the reaction, typically by obstructing the reaction site.  1, record 1, English, - steric%20hindrance

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Accumulation de groupements volumineux autour d'un centre réactionnel, qui en rend l'accès difficile.  1, record 1, French, - encombrement%20st%C3%A9rique

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

Nonbonded repulsions between atoms or groups of atoms in a molecule or transition state. For example, it is greater in cis-2-butene than in trans-2-butene because of the closeness of the two methyl groups in the former.  1, record 2, English, - steric%20hindrance

Record number: 2, Textual support number: 1 CONT

When an enzyme is immobilized by using a water-insoluble polymer carrier, the enzyme activity toward substrates of high molecular weight is markedly reduced due to steric hindrance which obstructs the approach of the substrate to the enzyme molecule. However, the activity of immobilized enzyme toward substrates of low molecular weight is similar to that of the native enzyme because the substrate can easily approach the enzyme molecule.  2, record 2, English, - steric%20hindrance

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Accumulation de groupements volumineux autour d'un centre réactionnel, qui en rend l'accès difficile.  1, record 2, French, - encombrement%20st%C3%A9rique

Record number: 2, Textual support number: 1 CONT

Tout comme il interagit avec la structure tridimensionnelle de l'enzyme, le microenvironnement imposé par l'immobilisation peut en modifier le comportement apparent pour des raisons purement mécaniques d'encombrement stérique. L'accessibilité des différents sites d'une enzyme est en effet fortement conditionnée par la méthode d'immobilisation choisie. La différence avec l'enzyme soluble est d'autant plus marquée que le substrat ou l'effecteur sont de taille plus importante.  2, record 2, French, - encombrement%20st%C3%A9rique

Record 2,  Textual support,  Spanish