TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

TOXIN THERAPY [1 record]

Record 1 2024-05-02

English

Subject field(s)
  • Non-Surgical Treatment
  • Pharmacology
CONT

Anthrax toxin proteins engineered to require activation by tumor-associated proteases show high specificity and potency in suppression of solid tumor growth through actions on tumor endothelial cells. The toxin strongly inhibits proliferation of tumor endothelial cells. Importantly, an immunosuppressive regimen (pentostatin plus cyclophosphamide) not only prevents induction of toxin-neutralizing antibodies, allowing multiple courses of toxin treatment, but also has strong synergy with the toxin on solid tumors.

French

Domaine(s)
  • Traitements non chirurgicaux
  • Pharmacologie
DEF

Emploi de toxines pour traiter certaines affections.

Spanish

Campo(s) temático(s)
  • Tratamiento sin cirugía
  • Farmacología
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