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VDRL ASSAY [1 record]

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Alphabetical list of terms

Record 1 2023-03-30

English

Subject field(s)
  • Diagnostic Procedures (Medicine)
  • Bacterial Diseases
DEF

The standard nontreponemal antigen serologic test for syphilis [that consists of] a slide flocculation test using heat-inactivated serum and VDRL antigen, a standardized mixture of cardiolipin, lecithin, and cholesterol.

CONT

Syphilitic infection leads to the production of nonspecific antibodies that react to cardiolipin. This reaction is the foundation of "non-treponemal" assays such as the VDRL (Venereal Disease Research Laboratory) test[, a] flocculation type [test that uses] an antigen-antibody interaction. The complexes remain suspended and therefore visible due to the lipid based antigens. With the VDRL a microscope is required ... The VDRL assay detects an antibody against cardiolipin, a cellular membrane component that is released by cells when they are damaged by T. [Treponema] pallidum or in some other medical conditions.

OBS

Although "VDRL" is widely used as synonym of "VDRL test," it is preferable to use the more precise terms to avoid any confusion.

OBS

VDRL test: This term appears under the entry "test" in the Dorland's illustrated medical dictionary.

French

Domaine(s)
  • Méthodes diagnostiques (Médecine)
  • Maladies bactériennes
CONT

Le diagnostic sérologique [de la syphilis] comprend un test de dépistage initial du sérum par des analyses non tréponémiques telles que le test VDRL (Venereal Disease Research Laboratory) [...]

CONT

VDRL -- Il repose sur l'agglutination passive des anticorps dirigés contre l'antigène cardiolipidique fixé sur un support inerte constitué de cristaux de cholestérol. La formation de complexes antigènes-anticorps provoque la formation de floculats visibles au microscope, à faible grossissement. Le VDRL est simple, rapide et peu coûteux.

OBS

Bien qu'on utilise souvent «VDRL» pour désigner la notion de «test VDRL», il est préférable d'utiliser «test VDRL» pour éviter toute confusion.

Spanish

Campo(s) temático(s)
  • Procedimientos diagnósticos (Medicina)
  • Enfermedades bacterianas
CONT

Prueba VDRL. En las personas seropositivas al VIH es importante la realización de este examen porque la presencia de otra ETS [enfermedades de transmisión sexual] puede activar al VIH, haciendo necesario dar de inmediato el tratamiento contra aquella.

OBS

VDRL por sus iniciales en inglés "Venereal Disease Research Laboratory".

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