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VIROSOME [1 record]

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Record 1 1997-03-14

English

Subject field(s)
  • Microbiology and Parasitology
CONT

Virosome Vectors for gene therapy. The long term goal of this work is to develop a targeted, efficient, liposome-based vector for the delivery and insertion of the CFTR gene to lung cells. To do this, a combination of liposometechnology and molecular biology will be used. Three observations have led us to propose the outlined research: (i) The efficiency of liposome fusion to cells or organelles can be greatly enhanced by incorporating viral fusion proteins intovesicles. (ii) After liposome-cell fusion, the contents of the liposomes are released into the cell's cytoplasm. (iii) By delivering DNA to nonlysosomal compartments of eukarvotic cells the efficiency of transfection can be greatly enhanced ...

OBS

Excerpt taken from Microsoft Internet Explorer.

French

Domaine(s)
  • Microbiologie et parasitologie
DEF

Liposome dans lequel des particules virales ont été introduites.

Spanish

Campo(s) temático(s)
  • Microbiología y parasitología
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