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streptozotocin [1 record]
Record 1 - internal organization data 2010-12-20
Record 1, English
Record 1, Subject field(s)
- Medication
Universal entry(ies) Record 1
Record 1, Main entry term, English
- streptozotocin
1, record 1, English, streptozotocin
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
a broad-spectrum antibiotic ... with antineoplastic and diabetogenic properties that has been isolated from a bacterium of the genus Streptomyces (S. achromogenes). 2, record 1, English, - streptozotocin
Record number: 1, Textual support number: 1 CONT
... it has been known for 35 years that the drug alloxan can destroy beta cells and induce diabetes in experimental animals. The drug is highly selective in its effects: damage to beta cells can be observed within minutes after injection. In the early 1960's another drug, streptozotocin, was also shown to be toxic to beta cells and capable of inducing diabetes in experimental animals. 1, record 1, English, - streptozotocin
Record number: 1, Textual support number: 1 OBS
Chemical formula: C8 H15 N3 O7 3, record 1, English, - streptozotocin
Record 1, French
Record 1, Domaine(s)
- Médicaments
Entrée(s) universelle(s) Record 1
Record 1, Main entry term, French
- streptozotocine
1, record 1, French, streptozotocine
feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
(...) on sait depuis 35 ans que l'alloxane détruit les cellules bêta et induit le diabète chez les animaux de laboratoire. Cette drogue a des effets très sélectifs : on peut observer une atteinte de cellules bêta dans les minutes qui suivent l'injection. Au début des années 1960, on a montré qu'une autre drogue, la streptozotocine, présente également une toxicité pour les cellules bêta et qu'elle est capable d'induire le diabète chez les animaux de laboratoire. 1, record 1, French, - streptozotocine
Record number: 1, Textual support number: 1 OBS
Formule chimique : C8 H15 N3 O7 2, record 1, French, - streptozotocine
Record 1, Spanish
Record 1, Textual support, Spanish
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