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MIXED LYMPHOCYTE REACTION [1 record]

Record 1 2006-05-09

English

Subject field(s)
  • Immunology
DEF

The transformation of small lymphocytes to blast cells following the mixing of lymphocytes from two individuals in a five-day culture. The number of blast cells produced varies inversely with the histocompatibility of the two donors.

French

Domaine(s)
  • Immunologie
DEF

Transformation blastique in vitro (apparition de lymphoblastes et de mitoses, incorporation accrue de thymidine) de lymphocytes en présence de lymphocytes allogéniques. On distingue les RLM bilatérales où les deux populations lymphocytaires réagissent l'une contre l'autre et les réactions unilatérales où l'une des deux populations (la population «stimulante») est inactivée par irradiation ou traitement par la mitomycine.

OBS

culture mixte de lymphocytes (J.-F. Bach, P. Lesavre. Op. citation page 365)

Spanish

Campo(s) temático(s)
  • Inmunología
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