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hémoglobine Bart [1 record]

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Record 1 2017-12-08

English

Subject field(s)
  • Diagnostic Procedures (Medicine)
  • Blood
DEF

A hemoglobin variant that is a tetramer of Y chains, a marker of alpha-thalassemia.

CONT

Although b-thalassemia is indistinguishable from normal electrophoresis done at early infancy, the diagnosis of clinically significant a-thalassemia syndrome is suggested by the presence of greater than 2% of Bart's hemoglobin, which aids in the differential diagnosis of hypochromic microcytic anemia late in infancy.

French

Domaine(s)
  • Méthodes diagnostiques (Médecine)
  • Sang
DEF

Hémoglobine anormale formée uniquement d'une chaîne Y, marqueur de la thalassémie alpha.

CONT

Lors de la délétion de 3 gènes a-globine ou hémoglobinose H, les chaînes g en excès se tétramérisent pour donner une hémoglobine appelée hémoglobine Bart (g4) lors de la période fœtale.

Spanish

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