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TERAPIA GENETICA SUBSTITUICAO [1 record]
Record 1 - internal organization data 2008-10-28
Record 1, English
Record 1, Subject field(s)
- Genetics
- Biotechnology
Record 1, Main entry term, English
- replacement gene therapy
1, record 1, English, replacement%20gene%20therapy
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
It is anticipated that replacement gene therapy would be most appropriate for autosomal or sex-linked recessive mutations where loss of the normal gene product results in disease. 2, record 1, English, - replacement%20gene%20therapy
Record 1, French
Record 1, Domaine(s)
- Génétique
- Biotechnologie
Record 1, Main entry term, French
- thérapie génique de remplacement
1, record 1, French, th%C3%A9rapie%20g%C3%A9nique%20de%20remplacement
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
Théoriquement, la thérapie génique peut revêtir plusieurs formes dont l'addition génique, la modification génique in situ et le remplacement génique. Cependant, dans les applications médicales actuelles du génie génétique, seule l'addition de gènes est praticable. 2, record 1, French, - th%C3%A9rapie%20g%C3%A9nique%20de%20remplacement
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
- Biotecnología
Record 1, Main entry term, Spanish
- terapia génica de sustitución
1, record 1, Spanish, terapia%20g%C3%A9nica%20de%20sustituci%C3%B3n
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- terapia génica de reemplazamiento 2, record 1, Spanish, terapia%20g%C3%A9nica%20de%20reemplazamiento
correct, feminine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
Las bases metodológicas de la terapia génica se sustentan en la inserción de un determinado gen [...] Así, el fin último de todo ello será reemplazar la función alterada, bien mediante la introducción del gen sano y completo, en cuyo caso hablaríamos de terapia génica de adición, o bien mediante la reparación puntual de la mutación con sondas oligonucleotídicas de ácido desoxirribonucleico (ADN) o ribonucleico (ARN), en cuyo caso procederíamos mediante terapia génica de sustitución. 3, record 1, Spanish, - terapia%20g%C3%A9nica%20de%20sustituci%C3%B3n
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