TERMIUM Plus^®

Fiche 1,  Justifications,  Anglais

Record number: 1, Textual support number: 1 CONT

Here we describe changes in dNTP metabolism that precede DNA fragmentation in a model of apoptosis driven by deprivation of the cytokine interleukin 3 (IL-3). In haemopoietic BAF3 cells, IL-3 withdrawal leads to a rapid decrease in the size of dATP, dTTP and dGTP pools without affecting dCTP levels. This imbalance in dNTP pools precedes DNA fragmentation and is accompanied by down-regulation of enzymes controlling the de novo and salvage pathways of dNTP synthesis, ribonucleotide reductase and thymidine kinase (TK) respectively.  2, fiche 1, Anglais, - dNTP

Record number: 1, Textual support number: 1 OBS

Biochemical Journal, Biochem. J. (1996) 316, 421 425 (Printed in Great Britain).  3, fiche 1, Anglais, - dNTP

Fiche 1,  Justifications,  Français

Record number: 1, Textual support number: 1 OBS

Précurseur utilisé pour la synthèse de l'ADN.  3, fiche 1, Français, - 2%2Dd%C3%A9soxyribonucl%C3%A9otide%20triphosphate

Fiche 1,  Justifications,  Espagnol