TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
LEAD COMPOUND [2 records]
Record 1 - internal organization data 2022-05-05
Record 1, English
Record 1, Subject field(s)
- Pharmacology
- Biotechnology
Record 1, Main entry term, English
- lead compound
1, record 1, English, lead%20compound
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- lead 2, record 1, English, lead
correct, noun
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
A lead is a compound or series of compounds with proven activity and selectivity in a screen and fulfills some drug development criteria such as originality, patentability, and accessibility (by extraction or synthesis). 3, record 1, English, - lead%20compound
Record 1, French
Record 1, Domaine(s)
- Pharmacologie
- Biotechnologie
Record 1, Main entry term, French
- composé tête de série
1, record 1, French, compos%C3%A9%20t%C3%AAte%20de%20s%C3%A9rie
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- composé chef de file 2, record 1, French, compos%C3%A9%20chef%20de%20file
correct, masculine noun
- tête de série 3, record 1, French, t%C3%AAte%20de%20s%C3%A9rie
correct, feminine noun
- chef de file 4, record 1, French, chef%20de%20file
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Substance pharmacologiquement active dont la structure chimique est modifiée de façon à engendrer une famille de substances pharmacologiquement plus actives ou mieux tolérées. 5, record 1, French, - compos%C3%A9%20t%C3%AAte%20de%20s%C3%A9rie
Record number: 1, Textual support number: 1 CONT
Une cible est habituellement une protéine qui joue un rôle fondamental dans le délai d'action ou de progression d'une maladie alors qu'une tête de série est un composé de synthèse d'une pharmacothèque (une «banque» de molécules) ayant une activité biologique intéressante, et qui, par ajustements successifs, donnera peut-être un nouveau médicament. 6, record 1, French, - compos%C3%A9%20t%C3%AAte%20de%20s%C3%A9rie
Record number: 1, Textual support number: 1 OBS
composé tête de série : désignation retenue par le réseau Entraide Traduction Santé. 7, record 1, French, - compos%C3%A9%20t%C3%AAte%20de%20s%C3%A9rie
Record number: 1, Textual support number: 2 OBS
tête de série; chef de file : désignations et définition publiées au Journal officiel de la République française le 28 janvier 2020. 8, record 1, French, - compos%C3%A9%20t%C3%AAte%20de%20s%C3%A9rie
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Farmacología
- Biotecnología
Record 1, Main entry term, Spanish
- compuesto candidato
1, record 1, Spanish, compuesto%20candidato
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Sustancia química que, sometida a pruebas preliminares, ha evidenciado que posee una actividad biológica prometedora. 1, record 1, Spanish, - compuesto%20candidato
Record 2 - internal organization data 1976-06-19
Record 2, English
Record 2, Subject field(s)
- Chemical Elements and Compounds
- Lead (Metallurgy)
Record 2, Main entry term, English
- lead compound 1, record 2, English, lead%20compound
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, French
Record 2, Domaine(s)
- Éléments et composés chimiques
- Plomb (Métallurgie)
Record 2, Main entry term, French
- composé de plomb
1, record 2, French, compos%C3%A9%20de%20plomb
masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record 2, Spanish
Record 2, Textual support, Spanish
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