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METAPLASIA [7 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2023-06-09

English

Subject field(s)
  • Morphology and General Physiology
  • Histology
DEF

The transformation of an epithelium, usually mucosal or glandular, to a stratified squamous epithelium.

CONT

When an air passage is irritated(like from smoking or infection), the cells lining it can change from being like rectangles standing up next to each other, to being flatter and stacked on top of each other. This change is called squamous metaplasia because the cells now look like the type of cells called squamous cells. When the irritation disappears, for example when you stop smoking or the infection clears, the lining cells return to their normal appearance. Squamous metaplasia is not considered a pre-cancer, but if the irritation persists it can progress to squamous dysplasia.

French

Domaine(s)
  • Morphologie et physiologie générale
  • Histologie

Spanish

Save record 1

Record 2 2012-03-01

English

Subject field(s)
  • Radiography (Medicine)
  • Musculoskeletal System
DEF

A reactive lesion occurring in soft tissues, at times near bone and periosteum, most often after trauma. The lesion is characterized by fibrous, osseous, and cartilaginous proliferation and metaplasia.

OBS

The term is a misnomer because often skeletal muscle is not involved and when involved it does not necessarily show inflammatory changes. In its early evolution, bone may not be identifiable on conventional radiography, but computed tomography and ultrasonography may show early signs of calcification in soft tissues.

French

Domaine(s)
  • Radiographie (Médecine)
  • Appareil locomoteur (Médecine)
DEF

Remaniement du tissu musculaire strié ou de tout autre tissu conjonctif associant une prolifération fibroblastique et des métaplasies cartilagineuses ou osseuses. D'origine le plus souvent post-traumatique, cette affection peut atteindre la surface externe d'un os ou les tissus mous, à distance de la surface périostée. Elle peut simuler un processus néoplasique. À la période d'état, l'aspect diagnostic est celui d'une formation osseuse comprenant une corticale et des travées osseuses. À un stade plus précoce, la radiographie ne montre pas les éléments calcifiés : il convient alors de recourir à la tomodensitométrie ou à l'échographie pour faire le diagnostic.

OBS

Le terme myosite ossifiante, quoique très largement adopté, est mauvais. Le tissu musculaire n'est pas nécessairement atteint dans cette lésion qui n'est pas inflammatoire. La lésion, apparaissant dans les tissus mous, est quelquefois dénommée tumeur osseuse pseudo-maligne des tissus mous. La myosite ossifiante est nettement distincte de l'affection rare et généralisée connue sous le nom de myosite ossifiante progressive.

Spanish

Save record 2

Record 3 2012-02-20

English

Subject field(s)
  • Symptoms (Medicine)
  • Cancers and Oncology
  • Bones and Joints
CONT

The myeloproliferative disorders comprise a group of usually neoplastic diseases, which may be related histogenetically by a common multipotential stem cell, that includes among others acute and chronic granulocytic leukemias, acute and chronic myelomonocytic leukemias, polycythemia vera, myelofibrosis, myeloid metaplasia, essential thrombocytemia, and erythroleukemia. An interrelationship with the lymphoproliferative disorders is thought to exist.

French

Domaine(s)
  • Symptômes (Médecine)
  • Cancers et oncologie
  • Os et articulations
DEF

Hémopathie caractérisée par une prolifération des cellules de la série myéloïde se produisant électivement au niveau de la moelle osseuse.

Spanish

Campo(s) temático(s)
  • Síntomas (Medicina)
  • Tipos de cáncer y oncología
  • Huesos y articulaciones
DEF

Término que designa cuatro trastornos sanguíneos diferentes, de los que sólo la leucemia mieloide crónica es cancerosa. Los otros son policitemia vera, metaplasia mieloide agnogénica y trombocitemia esencial.

CONT

Los hematólogos tratan los trastornos mieloproliferativos, de los que un número considerable acaban leucemia mieloide aguda.

Key term(s)
  • trastornos mieloproliferativos
Save record 3

Record 4 2011-02-18

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
Universal entry(ies)
C6H14O6S2
formula, see observation
C6H14S2O6
formula, see observation
DEF

A bifunctional cytotoxic alkylating agent, 1, 4-butanediol dimethanesulfonate, an antineoplastic agent unrelated to the nitrogen mustards; used primarily for treatment of chronic granulocytic leukemia and also polycythemia vera and myeloid metaplasia; the major side effect is bone marrow depression.

OBS

Chemical formula: C6H14O6S2 or C6H14S2O6

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
Entrée(s) universelle(s)
C6H14O6S2
formula, see observation
C6H14S2O6
formula, see observation
DEF

Poudre cristalline, insoluble dans l'eau, peu soluble dans l'alcool utilisé entre autres dans le traitement de la leucémie myéloïde.

OBS

Formule chimique : C6H14S2O6 ou C6H14O6S2

Spanish

Campo(s) temático(s)
  • Elementos y compuestos químicos
  • Medicamentos
Entrada(s) universal(es)
C6H14O6S2
formula, see observation
C6H14S2O6
formula, see observation
DEF

Fármaco alquilante antineoplásico.

OBS

[...] utilizado para el tratamiento de la leucemia mielógena crónica, y neoplasia de la médula ósea.

OBS

Fórmula química: C6H14O6S2 o C6H14S2O6

Save record 4

Record 5 2004-02-13

English

Subject field(s)
  • Cancers and Oncology
DEF

Carcinoma with chondromatous metaplasia.

French

Domaine(s)
  • Cancers et oncologie
DEF

Carcinome contenant des éléments cartilagineux.

Spanish

Save record 5

Record 6 1996-08-15

English

Subject field(s)
  • Bones and Joints
DEF

A condition in which cartilaginous loose bodies are formed by cartilage metaplasia of the synovial lining of joints and tendon sheaths.

CONT

This retrospective study concerns six patients in whom chondrosarcoma was suspected to develop in synovial chondromatosis.

French

Domaine(s)
  • Os et articulations
DEF

Métaplasie cartilagineuse des fibroblastes de l'intima synoviale, qui touche préférentiellement le genou. [D'après REVOR, 1996, vol. 82, no 3, p. 217]

Spanish

Save record 6

Record 7 1994-03-03

English

Subject field(s)
  • Biochemistry
  • Cytology
CONT

Increased intraplatelet levels of platelet-derived growth factor and transforming growth factor-beta in patients with myelofibrosis with myeloid metaplasia.

OBS

Tiré de: British Journal of Haematology, 1991, 77 (11), 80-86.

French

Domaine(s)
  • Biochimie
  • Cytologie
CONT

Comme pour la régulation des chaînes A et B du PDGF, très peu de choses sont connues sur la régulation des sous-unités du récepteur. Le TGF-bêta (transforming growth factor beta) diminue l'expression des ARNm de la sous-unité alpha et augmente celle de la sous-unité Bêta sur des fibroblastes murins.

Spanish

Save record 7

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