TERMIUM Plus^®

Fiche 1,  Justifications,  Anglais

Record number: 1, Textual support number: 1 CONT

The research project concerns characterization of the expression of the FMR-1 gene in various cultured cells under various conditions of growth or states of differentiation ... The research would be more appealing if it were focused on testing a specific hypothesis, particularly one related to the fragile syndrome phenotype or RNA processing ....  1, fiche 1, Anglais, - fragile%20X%20syndrome%20phenotype

Record number: 1, Textual support number: 2 CONT

Evidence that methylation of the FMR-I locus is responsible for variable phenotypic expression of the fragile X syndrome. DNA ... was analyzed ... using [a] probe in an unusual fragile X family with 6 brothers, three of whom are affected with fragile X to varying degrees. Fragile X chromosome studies, detailed physical examinations, and psychological testing were completed on all six ... The three affected males spanned the phenotypic and cognitive spectrum of the fragile X syndrome ... [Source: PASCAL database].  2, fiche 1, Anglais, - fragile%20X%20syndrome%20phenotype

Fiche 1,  Justifications,  Français

Record number: 1, Textual support number: 1 OBS

[syndrome X-fragile :] des anomalies cytogénétiques constantes peuvent être la marque distinctive d'un syndrome hérité comme une maladie monogénique. Tel est le cas par exemple du syndrome X-fragile, principale cause d'arriération mentale masculine génétiquement transmise.  2, fiche 1, Français, - ph%C3%A9notype%20du%20syndrome%20X%2Dfragile

Fiche 1,  Justifications,  Espagnol