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The human immunodeficiency virus (HIV) genome encodes at least seven groups of viral proteins. These groups of proteins include the three classes of polypeptides present in the majority of animal retroviruses: 1. structural, nonenvelope polypeptides encoded by the gag gene; 2. enzymes required for virion replication (reverse transcriptase/r) and for cleavage of viral precursor proteins (protease/pr), both encoded by the pol gene; 3. envelope polypeptides encoded by env gene. In addition, HIV's possess genes that encode four sets of polypeptides not found in the majority of typical retroviruses. These include a transactivating regulator of RNA translation (tat), a cis-acting downregulator of RNA transcription (nef), a regulator that modulates the expression of structural proteins (rev), a protein that modulates viral infectivity (vif), and two proteins (vpr,vpu) whose functions are still unclear. [From source a].  2, fiche 1, Anglais, - viral%20protein

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Both the core and envelope of HIV are composed of viral proteins. The core viral proteins include p24 and p18, and the envelope viral proteins include gp41 and gp120.  3, fiche 1, Anglais, - viral%20protein

Fiche 1,  Justifications,  Français

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Protéines virales. Les protéines du V.I.H.-1, toutes antigéniques, c'est-à-dire capables d'induire la production d'anticorps, se répartissent en : 1) Des protéines associées à la nucléocapside. Ce sont des protéines structurales internes liées aux unités d'ARN et formant avec elle la nucléoïde. 2) Des protéines d'enveloppes chargées de sucres (glycoprotéines) 3) De nombreuses autres protéines identifiées récemment et dont le rôle commence à être connu.  2, fiche 1, Français, - prot%C3%A9ine%20virale

Fiche 1,  Justifications,  Espagnol

Fiche 2,  Justifications,  Anglais

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A 96-amino acid (14 kd) protein, which is incorporated into the virion. It interacts with the p6gag part of the Pr55gag precursor. Vpr detected in the cell is localized to the nucleus. Proposed functions for Vpr include the nuclear import of preintegration complexes, cell growth arrest,transactivation of cellular genes, and induction of cellular differentiation. Found in HIV-1, HIV-2, SIVmac and SIVmnd. It is homologous to VPX of SIVagm.  2, fiche 2, Anglais, - viral%20protein%20u

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Glossary in molecular biology (Portions of the glossary text were taken directly or modified from definitions in the U.S. Congress Office of Technology Assessment document).  3, fiche 2, Anglais, - viral%20protein%20u

Fiche 2,  Justifications,  Français

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Une des protéines du rétrovirus HIV-1 qui participe avec la protéine Vif à la maturation du virus.  2, fiche 2, Français, - prot%C3%A9ine%20virale%20u

Fiche 2,  Justifications,  Espagnol

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Uno de los tres genes auxiliares del VIH [virus de la inmunodeficiencia humana].  1, fiche 2, Espagnol, - vpu

Fiche 3,  Justifications,  Anglais

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A 96-amino acid (14 kd) protein, which is incorporated into the virion. It interacts with the p6gag part of the Pr55gag precursor. the Vpr detected in the cell is localized to the nucleus. Proposed funtions for Vpr include the nuclear import of preintegration complexes, cell growth arrest, transactivation of cellular genes, and induction of cellular differentiation. Found in HIV-1, HIV-2, SIVmac and SIVmnd, It is homologous to VPX of SIVmgm.  2, fiche 3, Anglais, - virus%2Dencoded%20protein

Record number: 3, Textual support number: 1 OBS

Glossary of molecular biology (portions of the glossary text were taken directly or modified from definitions in the U.S. Congress Office of Technology Assessment document).  3, fiche 3, Anglais, - virus%2Dencoded%20protein

Fiche 3,  Justifications,  Français

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Le processus de transcription inverse commence pendant l'encapsidation de l'ARN. Il n'est pas initié par un ARN de transfert, comme chez les rétrovirus, mais par une protéine virale qui n'est autre que la polymérase.  3, fiche 3, Français, - prot%C3%A9ine%20virale

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Équivalents français approuvés par l'Unité de recherche en vaccinologie, Laboratoire et Service d'infectiologie, Centre hospitalier de l'université Laval (CHUL), Québec.  4, fiche 3, Français, - prot%C3%A9ine%20virale

Fiche 3,  Justifications,  Espagnol