TERMIUM Plus^®

Fiche 1,  Justifications,  Anglais

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The researchers who studied the German and Austrian patients ... had initially called the syndrome vaccine-induced prothrombotic immune thrombocytopenia; [two teams of researchers] now suggest a slightly simpler name: vaccine-induced immune thrombotic thrombocytopenia (VITT).  4, fiche 1, Anglais, - vaccine%2Dinduced%20immune%20thrombotic%20thrombocytopenia

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... the patients had unusual antibodies that trigger clotting reactions, which use up the body's platelets and can block blood vessels, leading to potentially deadly strokes or embolisms. The symptoms resemble a rare reaction to the drug heparin, called heparin-induced thrombocytopenia(HIT), in which the immune system makes antibodies to a complex of heparin and a protein called platelet factor 4(PF4), triggering platelets to form dangerous clots throughout the body.  4, fiche 1, Anglais, - vaccine%2Dinduced%20immune%20thrombotic%20thrombocytopenia

Fiche 1,  Justifications,  Français

Fiche 1,  Justifications,  Espagnol

Record number: 1, Textual support number: 1 CONT

La trombocitopenia trombótica inmunitaria inducida por vacunas (VITT, por sus siglas en inglés) se define como un síndrome clínico caracterizado por todas las anomalías de laboratorio y radiológicas descritas a continuación que ocurren en individuos de 4 a 30 días después de la vacunación con Ad26.COV2 (Johnson & Johnson) o ChAdOx1 nCoV-19(Oxford-A. Zeneca).  1, fiche 1, Espagnol, - trombocitopenia%20inmune%20tromb%C3%B3tica%20inducida%20por%20vacuna

Fiche 2,  Justifications,  Anglais

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Ordinarily, heparin prevents clotting and does not affect the platelets, components of the blood that help form blood clots. Triggered by the immune system in response to heparin, HIT causes a low platelet count(thrombocytopenia).  2, fiche 2, Anglais, - heparin%2Dinduced%20thrombocytopenia

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Fiche 2,  Justifications,  Espagnol

Record number: 2, Textual support number: 1 DEF

Reacción adversa protrombótica, mediada por activación de anticuerpos antiplaquetarios (mayoritariamente IgG [inmonoglobulinas G) contra el complejo formado por el factor plaquetario y la heparina, en individuos en tratamiento con este fármaco.  1, fiche 2, Espagnol, - trombocitopenia%20inducida%20por%20heparina

Fiche 3,  Justifications,  Anglais

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Heparin-induced thrombocytopenia with thrombosis(HITT) is a paradoxical prothrombotic complication of anticoagulant therapy. As many as 3% of patients undergoing cardiac surgery develop clinical HIT [heparin-induced thrombocytopenia] presenting as thrombocytopenia with or without thrombosis within 5–10 days of heparin exposure. Thrombotic complications associated with HIT carry a mortality rate of 5–10%.  2, fiche 3, Anglais, - heparin%2Dinduced%20thrombocytopenia%20with%20thrombosis

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Fiche 3,  Justifications,  Espagnol

Fiche 4,  Justifications,  Anglais

Record number: 4, Textual support number: 1 DEF

A cutaneous reaction in which an area of skin previously exposed to an intradermal endotoxin undergoes hemorrhagic necrosis if the animal receives, 18 to 36 hours later, a small intravenous dose of endotoxin. The platelets, and neutrophils does not involve antibodies, and can be prevented by aspirin or heparin.  1, fiche 4, Anglais, - Shwartzman%20phenomenon

Fiche 4,  Justifications,  Français

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Réaction (apparemment non immunologique) nécrotique, locale ou systémique (et pouvant alors intéresser les reins, les poumons, le foie et le cœur), consécutive à l'administration d'une injection d'endotoxine chez un sujet sensibilisé par une première injection de la même ou d'une autre endotoxine.  1, fiche 4, Français, - r%C3%A9action%20de%20Shwartzman

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Fiche 5,  Justifications,  Anglais

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The first nonthrombogenic surface for biomedical implants, using the natural anticoagulant heparin in a coating process, was described in 1963. Despite a vigorous search for additional synthetic thromboresistant materials, substitute heart valves have benefited most from empirical selection of a cobalt-chromium alloy, Stellite 21, which showed excellent thromboresistance...  1, fiche 5, Anglais, - thromboresistance

Fiche 5,  Justifications,  Français

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[...] des électrets ont été utilisés avec succès comme prothèses vasculaires compatibles avec le sang. En particulier des greffes d'implants chargés électronégativement ont montré que la thromborésistance (la résistance à la formation de caillots sanguins) était d'autant plus forte que la charge négative augmentait.  2, fiche 5, Français, - thrombor%C3%A9sistance

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Fiche 6,  Justifications,  Anglais

Record number: 6, Textual support number: 1 OBS

The most important therapy for patients with deep vein phlebitis is anticoagulation. Heparin must be used, for oral anticoagulants are not effective for several days. Its principal mode of action is activation of antithrombin III.  2, fiche 6, Anglais, - heparin%20therapy

Fiche 6,  Justifications,  Français

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L'héparinothérapie est, dans l'ensemble, très bien tolérée. Les complications dues au médicament lui-même doivent être distinguées des complications hémorragiques.  2, fiche 6, Français, - h%C3%A9parinoth%C3%A9rapie

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Fiche 7,  Justifications,  Anglais

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Any class of basic proteins of low molecular weight, occurring in combination with nucleic acids in the sperm of salmon and certain other fish and having the property of neutralizing heparin.  2, fiche 7, Anglais, - protamine

Fiche 7,  Justifications,  Français

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Protéine riche en acides diaminés, et presque complètement dépourvue d'acide aspartique et d'acide glutamique.  2, fiche 7, Français, - protamine

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Fiche 8,  Justifications,  Anglais

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The activated partial thromboplastin time(APTT) is a commonly performed laboratory procedure which is used for multiple purposes including monitoring of heparin therapy, detection of coagulation factor deficiency, and detection of lupus anticoagulants. Among the hereditary coagulation deficiencies, factor VIII and factor IX are the most common. APTT reagents differ widely in both their sensitivity to factor VIII and factor IX deficiencies as well as their responsiveness.  1, fiche 8, Anglais, - activated%20partial%20thromboplastin%20time%20reagent

Fiche 8,  Justifications,  Français

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Réactif utilisé pour déterminer le temps de coagulation du plasma sanguin.  2, fiche 8, Français, - r%C3%A9actif%20pour%20la%20d%C3%A9termination%20du%20temps%20de%20thromboplastine%20partielle%20activ%C3%A9e

Fiche 8,  Justifications,  Espagnol

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Reactivo utilizado para medir el tiempo de coagulación extrínseco del plasma.  4, fiche 8, Espagnol, - reactivo%20de%20tiempo%20de%20tromboplastina%20parcial%20activado

Fiche 9,  Justifications,  Anglais

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Prevention of postoperative thromboembolic complications, a prospective comparison between dextran 70, dihydroergotamin heparin and a sulphated polysaccharide.  1, fiche 9, Anglais, - sulphated%20polysaccharide

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Fiche 10,  Justifications,  Anglais

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Decrease in frequency of anginal episodes by control of thrombin generation with low-dose heparin : a controlled cross-over randomized study.  2, fiche 10, Anglais, - randomized%20study

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Fiche 10,  Justifications,  Espagnol

Fiche 11,  Justifications,  Anglais

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My reseach concentrates in the area of human biochemical and molecular genetic studies of lysosomal enzymes involved in dermatan sulfate, heparin, and heparin sulfate degradation. A deficiency in any one of the enzymes causes a human genetic lysosomal storage disease known as mucopolysaccharidosis.  3, fiche 11, Anglais, - lysosomal%20storage%20disease

Fiche 11,  Justifications,  Français

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Les maladies lysosomales sont des affections monogéniques dues au déficit des enzymes intralysosomales impliquées dans le catabolisme de macromolécules. Leur gravité clinique est l'absence, pour la plupart d'entre elles, de traitement efficace rendant prioritaires les tentatives de mises au point de thérapies géniques.  1, fiche 11, Français, - maladie%20lysosomale

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Fiche 12,  Justifications,  Anglais

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What is Arrow's recommended protocol for catheter heparinization and recommended heparin concentration? To maintain patency of the catheter between treatments, a heparin lock is usually instilled in each lumen of the catheter. The concentration of heparin, or alternative anticoagulant, should be determined by hospital protocol or physician order.  1, fiche 12, Anglais, - catheter%20heparinization

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Fiche 12,  Justifications,  Espagnol

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[Técnica que] tiene por objetivo la prevención de la coagulación del catéter.  1, fiche 12, Espagnol, - heparinizaci%C3%B3n%20de%20cat%C3%A9ter

Fiche 13,  Justifications,  Anglais

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Nine patients(69%) were receiving subcutaneous injection of heparin, three(23%) oral anticoagulant therapy and one continuous IV infusion of heparin.  1, fiche 13, Anglais, - continuous%20IV%20infusion

Fiche 13,  Justifications,  Français

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L'héparine est administrée par voie parentérale selon trois modalités. - La perfusion intraveineuse continue, rendue possible par l'utilisation d'une seringue électrique autopousseuse, assure une héparinémie constante.  1, fiche 13, Français, - perfusion%20intraveineuse%20continue

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intraveineuse : Cette graphie, puisée des Rectifications de l'orthographe recommandées par le Conseil supérieur de la langue française, est attestée dans le Petit Robert (2004).  2, fiche 13, Français, - perfusion%20intraveineuse%20continue

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Fiche 14,  Justifications,  Anglais

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Blood can be drawn from a peripheral IV if necessary, but only if it is in a relatively large vein and only if the IV is newly inserted. Originally, a peripheral IV was simply a needle that was taped in place and connected to tubing rather than to a syringe. Today, hospitals use a safer system in which the catheter is a flexible plastic tube that originally contains a needle to allow it to pierce the skin; the needle is then removed and discarded, while the soft catheter stays in the vein.  4, fiche 14, Anglais, - peripheral%20IV

Record number: 14, Textual support number: 2 CONT

Heparin therapy was discontinued, and the patient received 100 mg of tissue plasminogen activator(rt-PA [Alteplase]) by peripheral intravenous infusion over 2 hours.  3, fiche 14, Anglais, - peripheral%20IV

Fiche 14,  Justifications,  Français

Record number: 14, Textual support number: 1 OBS

intraveineuse : Cette graphie, puisée des Rectifications de l'orthographe recommandées par le Conseil supérieur de la langue française, est attestée dans le Petit Robert (2004).  3, fiche 14, Français, - perfusion%20intraveineuse%20p%C3%A9riph%C3%A9rique

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Fiche 15,  Justifications,  Anglais

Record number: 15, Textual support number: 1 CONT

Lovenox is manufactured from UFH [unfractionated heparin] by way of a salification process, an esterification process, and a depolymerization process of 3-elimination of uronic benzylic esters by alkaline media.  2, fiche 15, Anglais, - 3%2Delimination%20of%20uronic%20benzylic%20esters

Fiche 15,  Justifications,  Français

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Il faut considérer qu'il y a plusieurs esters et plusieurs acides uroniques dans UFH (probablement «unfractionated heparin»), donc : élimination en 3 d'esters benzyliques d'acides uroniques (en milieu alcalin).  1, fiche 15, Français, - %C3%A9limination%20en%203%20d%27esters%20benzyliques%20d%27acides%20uroniques

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Fiche 16,  Justifications,  Anglais

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A sulfated glycosaminoglycan of mixed polysaccharide nature varying in molecular weights and composed of polymers of alternating derivatives of D-glycosamine and L-iduronic acid or D-glucuronic acid.  2, fiche 16, Anglais, - heparin

Record number: 16, Textual support number: 1 OBS

It is released by mast cells and by basophils of the blood and is present in many tissues, especially the liver and lungs. Heparin is a mixture of active principles, some of which have potent anticoagulant properties that result from binding to and greatly enhancing the activity of antithrombin III and from inhibition of a number of coagulation factors, particularly activated factor X(factor Xa). Heparin also has lipotrophic properties, promoting transfer of fat from the blood to the fat depots by activation of lipoprotein lipase.  2, fiche 16, Anglais, - heparin

Fiche 16,  Justifications,  Français

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Polysaccharide hautement sulfaté produit par les granulocytes basophiles du sang circulant et leurs dérivés tissulaires les mastocytes. Utilisé en thérapeutique comme anticoagulant.  2, fiche 16, Français, - h%C3%A9parine

Fiche 16,  Justifications,  Espagnol

Record number: 16, Textual support number: 1 DEF

Ácido orgánico presente en los tejidos de los mamíferos. Inhibe la coagulación de la sangre. Polvo amorfo, blanco, higroscópico, soluble en agua.  2, fiche 16, Espagnol, - heparina

Fiche 17,  Justifications,  Anglais

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A purified mixture of simple protein principles from the sperm or testes of suitable species of fish; it is a heparin antagonist used in certain hemorrhagic states associated with increased amounts of heparin-like substances in the circulation and for the treatment of heparin overdosage.  2, fiche 17, Anglais, - protamine%20sulfate

Fiche 17,  Justifications,  Français

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Antidote de l'héparine : libération des complexes héparine-antithrombine III et formation de complexes héparine-protamine. Indications Hémorragie sévère par surdosage en héparine.  2, fiche 17, Français, - sulfate%20de%20protamine

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Fiche 18,  Justifications,  Anglais

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As in "heparin coating chemical".  2, fiche 18, Anglais, - heparin

Fiche 18,  Justifications,  Français

Record number: 18, Textual support number: 1 CONT

Si l'on reste fidèle au thromboélastogramme, les critères d'efficacité du traitement héparinique sont: "r + k" entre 50 et 60 mm et "a m" entre 35 et 40 mm.  2, fiche 18, Français, - h%C3%A9parinique

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Fiche 19,  Justifications,  Anglais

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A wing-tipped needle or plastic catheter fitted with an injection port, which must be flushed with a heparin solution to keep it free of clots once IV bolus or piggyback medication has been administered.  1, fiche 19, Anglais, - heparin%20lock

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Fiche 20,  Justifications,  Anglais

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The introduction of substance (drug, solution etc.) into a vessel, cavity, or tissue of the body.  2, fiche 20, Anglais, - injection

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Heparin may be administered intravenously by bolus injection, continuous infusion, or subcutaneous injection.  3, fiche 20, Anglais, - injection

Fiche 20,  Justifications,  Français

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Introduction d'une substance étrangère dans l'organisme.  2, fiche 20, Français, - injection

Record number: 20, Textual support number: 1 PHR

Injection vaginale, urétrale, intra-utérine, intra(-)veineuse [IV], de rappel, de sérum.  2, fiche 20, Français, - injection

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Fiche 21,  Justifications,  Anglais

Record number: 21, Textual support number: 1 CONT

If relatively large doses have been employed, it may be necessary when reinstituting anticoagulant therapy to use somewhat larger doses of the prothrombin depressing anticoagulant, or to use one which acts on a different principle, such as heparin sodium.  1, fiche 21, Anglais, - heparin%20sodium

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Une résistance temporaire aux anticoagulants dépresseurs de la prothrombine peut se manifester, surtout quand on emploie de fortes doses de vitamine K1. Dans ce dernier cas, à la reprise de l'anticoagulothérapie, il peut être nécessaire d'employer le dépresseur de prothrombine à doses plus élevées ou d'employer un anticoagulant agissant d'après un principe différent comme l'héparine sodique.  2, fiche 21, Français, - h%C3%A9parine%20sodique

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Fiche 22,  Justifications,  Anglais

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Haemodialysis units(HD) including : dialyzers, monitors, blood pumps, heparin pumps, air detectors.  1, fiche 22, Anglais, - haemodialysis%20unit

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ISO code: 03 15 03.  2, fiche 22, Anglais, - haemodialysis%20unit

Fiche 22,  Justifications,  Français

Record number: 22, Textual support number: 1 CONT

Matériels d'hémodialyse (HD) comprenant : les dialyseurs, les moniteurs, les pompes à sang, les pompes à héparine, les détecteurs d'air  1, fiche 22, Français, - mat%C3%A9riel%20d%27h%C3%A9modialyse

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Code ISO : 03 15 03.  2, fiche 22, Français, - mat%C3%A9riel%20d%27h%C3%A9modialyse

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Fiche 23,  Justifications,  Anglais

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A standard solution of heparin sodium labelled to indicate it is intended for maintenance of patency as intravenous injection devices only, and is not to be used for anticoagulant therapy.  3, fiche 23, Anglais, - heparin%20lock%20flush%20solution

Fiche 23,  Justifications,  Français

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Solution qui, après administration d'un médicament, sert à empêcher la formation de caillots dans le dispositif d'injection intermittente.  1, fiche 23, Français, - solution%20de%20rin%C3%A7age%20h%C3%A9parin%C3%A9e

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Fiche 24,  Justifications,  Anglais

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EMINASE SmithKline Beecham Anistreplase Fibrinolytic Agent There was significantly(p <0. 01, two sample t-test) higher left ventricular ejection fraction(LVEF) for the Eminase treatment group(53%) compared with the heparin treatment group(47. 5%) when measured 4 days after treatment(intent-to-treat analysis).  1, fiche 24, Anglais, - intent%2Dto%2Dtreat%20analysis

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Fiche 25,  Justifications,  Anglais

Record number: 25, Textual support number: 1 OBS

A method of giving anticoagulant medication during hemodialysis that involves adding heparin(the anti-coagulant) to the blood as it leaves the body, and neutralizing the heparin before it returns to the bloodstream. no. 187933 p. 38.  1, fiche 25, Anglais, - regional%20heparinization

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Source: EIST volume 10 page 765. EMC volume 43 36.920 A-40 page 6. Auteur: 2HU.  1, fiche 25, Français, - h%C3%A9parinisation%20r%C3%A9gionale

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Fiche 26,  Justifications,  Anglais

Record number: 26, Textual support number: 1 OBS

Opening in an intravenous fluid bag.  2, fiche 26, Anglais, - additive%20port

Record number: 26, Textual support number: 2 OBS

It was found that the total dose of heparin injected into the plastic bag remained in the additive port because the dead space between 2 diaphragms prevented injection with a 5/8 inch needle.(abstract)(Plastic IV bag problem with heparin administration-Drug Intell. Clin. Pharm. 16 : 410-411(May)(1982]  3, fiche 26, Anglais, - additive%20port

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