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Fiche 1,  Justifications,  Anglais

Record number: 1, Textual support number: 1 DEF

Gene that affects the incubation period in mice carrying the PrP gene.  2, fiche 1, Anglais, - scrapie%20incubation%20gene

Record number: 1, Textual support number: 1 OBS

It has two alleles: s7 for short incubation and p7 for prolonged incubation.  2, fiche 1, Anglais, - scrapie%20incubation%20gene

Fiche 1,  Justifications,  Français

Record number: 1, Textual support number: 1 DEF

Gène qui gouverne la période d'incubation chez les souris transgéniques exprimant le gène PrP.  1, fiche 1, Français, - g%C3%A8ne%20scrapie%20incubation

Record number: 1, Textual support number: 1 OBS

Il comprend deux allèles : s7 (s pour short, période d'incubation courte) et p7 (p pour prolonged, incubation longue).  1, fiche 1, Français, - g%C3%A8ne%20scrapie%20incubation

Fiche 1,  Justifications,  Espagnol

Fiche 2,  Justifications,  Anglais

Record number: 2, Textual support number: 1 CONT

The silent period that follows infection by the human immunodeficiency virus(HIV-1) and precedes seroconversion remains a problem for the screening of blood supply, and knowledge about the mechanism involved in the maintenance of latency is only fragmentary. Using purified nef recombinant protein and six synthetic nef peptides, antibodies to the product of an HIV-1 regulatory gene, the negative regulatory factor(nef) involved in maintenance of proviral latency, were detected by Western blot and radioimmunoassay techniques in HIV-1-seronegative, viral antigen-negative, and virus culture-negative individuals at risk for HIV infection.  2, fiche 2, Anglais, - negative%2Dregulatory%20factor

Record number: 2, Textual support number: 1 OBS

Tiré de la base de donnée: Index Medicus.  2, fiche 2, Anglais, - negative%2Dregulatory%20factor

Fiche 2,  Justifications,  Français

Record number: 2, Textual support number: 1 CONT

Le virus de l'immunodéficience humaine (HIV) présente une organisation génomique complexe, avec l'identification à ce jour de dix gènes codant pour des protéines structurales et régulatrices de l'expression génique virale. Parmi les protéines de régulation, Nef ou negative-regulatory factor (précédemment nommée 3'orf, orf-B, E' ou F) ne semble pas indispensable à la réplication et aux effets cytopathogènes du HIV.  1, fiche 2, Français, - prot%C3%A9ine%20de%20r%C3%A9gulation%20NEF

Fiche 2,  Justifications,  Espagnol

Fiche 3,  Justifications,  Anglais

Record number: 3, Textual support number: 1 DEF

The expression of genes by genetic transcription into complementary RNA sequences and, in the case of structural genes, the subsequent translation of messenger RNA into polypeptide chains which form the ultimate protein products of gene action (primary gene action).  1, fiche 3, Anglais, - gene%20action

Record number: 3, Textual support number: 1 CONT

Gene action is called "cell-specific" if the expression of a particular gene is limited to a definite cell system, and "phase-specific" if the manifestation is limited to a definite developmental period. Both phenomena are consequences of differential gene activation. The action of a particular gene is "sex-limited" if the corresponding phenotypic character is realized in only one of the sexes. "Sex-controlled" gene action is a type of action characterized by the different expression of a gene in male and female organisms. Genes showing either sex-limited or sex-controlled manifestation may be localized either in sex-chromosomes or autosomes.  1, fiche 3, Anglais, - gene%20action

Fiche 3,  Justifications,  Français

Fiche 3,  Justifications,  Espagnol