TERMIUM Plus^®

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Monkeypox virus belongs to the Orthopoxvirus genus in the family Poxviridae. The Orthopoxvirus genus also includes variola virus(which causes smallpox), vaccinia virus(used in the smallpox vaccine), and cowpox virus.  3, fiche 1, Anglais, - monkeypox%20virus

Fiche 1,  Justifications,  Français

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Après l'éradication de la variole, l'arrêt de la vaccination a favorisé la transmission à l'homme du virus de la variole du singe.  4, fiche 1, Français, - virus%20de%20la%20variole%20simienne

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Eczema caused by the herpes simplex virus, the vaccinia virus, or varicella zoster.  2, fiche 2, Anglais, - eczema%20vaccinatum

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Eczema vaccinatum is sometimes a serious complication, which may occur in vaccinated persons with active or healed eczema, or in subjects in contact with recent vaccinees. The disease tends to localize at sites where eczematous lesions are or have been present.  1, fiche 2, Anglais, - eczema%20vaccinatum

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Eczéma dû au virus de la vaccine.  1, fiche 2, Français, - ecz%C3%A9ma%20vaccinal

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Vaccinia virus is grown in tissue culture or on the scarified flank of a calf. After purification and the addition of stabilizing agents, the suspension is freeze-dried. Inoculated intradermally, vaccinia virus induces a mild infection and confers protection against all orthopoxviruses known to infect humans monkeypox, variola, and cowpox.  2, fiche 3, Anglais, - vaccinia%20virus

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Le virus de la vaccine [un poxvirus] est utilisé comme virus vecteur de vaccins recombinants : on insère dans le virus vaccinal le gène codant des protéines vaccinantes d'autres virus : hépatite B, rage, rougeole et on inocule ce néo-virus recombinant qui suscite l'apparition d'anticorps protecteurs.  2, fiche 3, Français, - virus%20de%20la%20vaccine

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Poxvirus vacuno usado como vector en el desarrollo de las vacunas VIH, para transportar genes del retrovirus en el organismo.  2, fiche 3, Espagnol, - virus%20de%20vaccinia

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A cloning vehicle which has a single cleavage site for one or more restriction endonucleases, thus allowing the insertion of a fragment of foreign DNA.  2, fiche 4, Anglais, - insertion%20vector

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Avipoxviruses, including Fowlpoxvirus(FPV) have been shown previously to infect mammalian cells but are unable to complete their replication cycle. Avipoxvirus based rabies and HIV vaccines have shown promise in preclinical studies. We have begun work to develop the FPV system for application to HPV CTL. We first constructed a new FPV insertion vector(Fig. 3) which facilitates production of recombinant viruses by co-insertion of the gpt marker gene under the control of a vaccinia virus 19K promoter. The gene of interest is inserted into a polylinker downstream of the vaccinia virus 7. 5K promoter.  3, fiche 4, Anglais, - insertion%20vector

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Vecteur de clonage ne comportant qu'un seul site de coupure pour une enzyme de restriction donnée, permettant ainsi l'insertion d'un fragment d'ADN étranger.  2, fiche 4, Français, - vecteur%20d%27insertion

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Ockenhouse, C. F. [...] et al. Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum Malaria. "Journal of Infectious Diseases, June 1998;177(6) : 1664-1673. According to the authors’ abstract of an article published in Journal of Infectious Diseases, "Candidate malaria vaccines have failed to elicit consistently protective immune responses against challenge with Plasmodium falciparum. NYVAC-Pf7, a highly attenuated vaccinia virus with 7 P. falciparum genes inserted into its genome, was tested in a Phase I/IIa safety, immunogenicity, and efficacy vaccine trial in human volunteers. Malaria genes inserted into the NYVAC genome encoded proteins from all stages of the parasite's life cycle.  1, fiche 5, Anglais, - multiantigen%20vaccine

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Grâce aux vaccins multi-antigènes, une piqûre «six-en-un» et le tour est joué.  1, fiche 5, Français, - vaccin%20multi%2Dantig%C3%A8nes

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Nodavirus RNA Replication. We have constructed DNA plasmids and vaccinia virus recombinants that express the RNA replicase of a nodavirus. In the cytoplasm of transfected or infected mammalian cells, this enzyme selectively amplifies its own mRNA by RNA replication. The replicase can also amplify other RNAs if they contain appropriate cis-acting replication signals, and we are striving to harness this ability for vector, vaccine, and gene therapy application.  1, fiche 6, Anglais, - RNA%20replicase

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Enzyme qui, chez les Virus à ARN, catalyse la reproduction (réplication) de cette molécule. Comme l'ARN viral est monocaténaire, la réplication nécessiterait un intermédiaire bicaténaire à partir duquel s'effectuerait la reproduction du brin.  2, fiche 6, Français, - ARN%20r%C3%A9plicase

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Karayiannis P, Saldanha J, Jackson AM, Luther S, Goldin R, Monjardino J, Thomas HC. Partial control of hepatitis delta virus superinfection by immunisation of woodchucks(Marmota monax) with hepatitis delta antigen expressed by a recombinant vaccinia or baculovirus. J Med Virol 1993; 41 : 2104  3, fiche 7, Anglais, - hepatis%20delta%20antigen

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Le génome du virus de l'hépatite D est constitué d'un ARN circulaire long de 1,7 kilobase qui code une phospholipoprotéine nucléaire, la HDAg (hepatitis delta antigen). Celle-ci se fixe spécifiquement sur l'ARN viral et est indispensable à la réplication du virus.  1, fiche 7, Français, - HDAg

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Génétique moléculaire.  2, fiche 7, Français, - HDAg

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