TERMIUM Plus^®

Fiche 1,  Justifications,  Anglais

Record number: 1, Textual support number: 1 CONT

High aspect ratio, or fiber-shaped, nanoparticles(HARNs), represent a growth area in nanotechnology as their useful properties become more apparent. Carbon nanotubes, the best known and studied of the HARNs, are handled on an increasingly large scale, with subsequent potential for human inhalation exposure. Their resemblance to asbestos fibers precipitated fears that they might show the same type of pathology as that caused by asbestos and there is emerging evidence to support this possibility. The large number of other HARNs, including nanorods, nanowires and other nanofibers, require similar toxicological scrutiny. In this article, we describe the unusual hazard associated with fibers, with special reference to asbestos, and address the features of fibers that dictate their pathogenicity as developed in the fiber pathogenicity paradigm. This paradigm is a robust structure-toxicity model that identifies thin, long, biopersistent fibers as the effective dose for fiber-type pathogenic effects. It is likely that HARNs will in general conform to the paradigm and such an understanding of the features that make fibers pathogenic should enable us to design safer HARNs.  3, fiche 1, Anglais, - high%20aspect%20ratio%20nanoparticle

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(Nanowerk News) A UK consortium of scientists, led by the Institute of Occupational Medicine, Edinburgh, has published a key report examining whether high aspect ratio nanoparticles (HARN) should raise the same concerns as asbestos fibres. HARN includes materials such as carbon nanotubes (CNT) and metal nanowires. The review, which was published by DEFRA [Department for Environment, Food and Rural Affairs] this week, identified many similarities between HARN and asbestos with regard to their physico-chemical properties and toxicological effects, and it concluded that there is sufficient evidence to suggest that HARN, which have the same characteristics (diameter, length and biopersitance) as pathogenic fibres such as asbestos, are likely to have similar pathology.  4, fiche 1, Anglais, - high%20aspect%20ratio%20nanoparticle

Record number: 1, Textual support number: 1 OBS

HARNs: plural.  2, fiche 1, Anglais, - high%20aspect%20ratio%20nanoparticle

Fiche 1,  Justifications,  Français

Record number: 1, Textual support number: 1 CONT

Les nano-objets sont des structures fabriquées volontairement dont une, deux ou trois dimensions extérieures sont de l’ordre nanométrique (entre 1 et 100 nm environ). Les nanoparticules et les nanofibres (respectivement trois et deux dimensions extérieures nanométriques) sont deux catégories importantes de nano-objets. Les nanoparticules sont obtenues par réduction de grosses particules ou par synthèse. Les nanofibres peuvent également avoir une forme tubulaire, tels les nanotubes de carbone; ces derniers peuvent être monoparoi (ou monofeuillet, SWCNT en anglais pour Single-Walled Carbon Nanotubes) ou multiparois (ou multifeuillets, MWCNT en anglais pour Multi-Walled Carbon Nanotubes). Pour les nanofibres, lorsque le rapport entre la longueur et le diamètre est élevé, on parle de nanoparticules à fort aspect ratio (HARN en anglais pour High Aspect Ratio Nanoparticles).  2, fiche 1, Français, - nanoparticule%20%C3%A0%20rapport%20d%27%C3%A9longation%20%C3%A9lev%C3%A9

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Le diamètre des nanoparticules varie du nanomètre à quelques dizaines de nanomètres, et leur longueur, du micromètre à plusieurs millimètres. Ces dimensions leur confèrent un rapport d'élongation (longueur sur diamètre) élevé, ainsi que des propriétés toxicologiques similaires à celles de l'amiante.  1, fiche 1, Français, - nanoparticule%20%C3%A0%20rapport%20d%27%C3%A9longation%20%C3%A9lev%C3%A9

Fiche 1,  Justifications,  Espagnol

Fiche 2,  Justifications,  Anglais

Record number: 2, Textual support number: 1 CONT

Following the phase of hazard identification, hazard characterization and food intake assessment, an integrated toxicological evaluation will combine all the information in relation to the food safety of the complex GM [genetically modified] animal-derived food product. This integrated toxicological evaluation needs to identify food safety issues that may require additional investigation, including traditional toxicity testing.  2, fiche 2, Anglais, - integrated%20toxicological%20evaluation

Fiche 2,  Justifications,  Français

Record number: 2, Textual support number: 1 CONT

Après la phase d'identification et de caractérisation des dangers et d'étude de l'ingestion alimentaire, une évaluation toxicologique intégrée combinera toutes les informations relatives à la sécurité sanitaire des denrées alimentaires complexes issues d'animaux génétiquement modifiés. Cette évaluation devra déterminer quelles sont les questions de sécurité sanitaire pouvant nécessiter des études supplémentaires, y compris des études de toxicité classiques.  2, fiche 2, Français, - %C3%A9valuation%20toxicologique%20int%C3%A9gr%C3%A9e

Fiche 2,  Justifications,  Espagnol

Fiche 4,  Justifications,  Anglais

Record number: 4, Textual support number: 1 CONT

A supplier MSDS [material safety data sheet] must have at least 9 sections with the following or similar headings.... 1. Product Information : to identify the product, the supplier/manufacturer, and to describe the use of the product. 2. Hazardous Ingredients... 3. Physical Data... 4. Fire or Explosion Hazard... 5. Reactivity Data... 6. Toxicological Properties... 7. Preventive Measures... 8. First Aid Measures... 9. Preparation Information....  2, fiche 4, Anglais, - product%20information

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Product Information: product identifiers, manufacturer and suppliers names, addresses and emergency phone numbers.  3, fiche 4, Anglais, - product%20information

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Fiche 4,  Justifications,  Espagnol

Fiche 5,  Justifications,  Anglais

Record number: 5, Textual support number: 1 CONT

The effect of exposure to some contaminants may be severe in a very short period of time (a few minutes or an hour or two). This is an acute hazard. This may pose an imminent threat to life. Strict procedures are required to safely deal with such situations.  1, fiche 5, Anglais, - acute%20hazard

Fiche 5,  Justifications,  Français

Fiche 5,  Justifications,  Espagnol

Fiche 6,  Justifications,  Anglais

Record number: 6, Textual support number: 1 CONT

When an emergency call is received by CANUTEC, the Emergency Response Advisor on duty ... recommends appropriate response actions for ... the stabilization and containment of the dangerous goods involved. The advisor provides technical information regarding the physical, chemical, toxicological and other properties of the products involved; recommends remedial actions for fires, spills or leaks;  2, fiche 6, Anglais, - toxicological%20property

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"hazard information" means information on the proper and safe storage, handling and use of a controlled product and includes information relating to its toxicological properties.  3, fiche 6, Anglais, - toxicological%20property

Fiche 6,  Justifications,  Français

Record number: 6, Textual support number: 1 CONT

Lorsque CANUTEC reçoit un appel d'urgence, le conseiller en interventions (...) propose les mesures à adopter afin (...) de stabiliser et de conteneuriser les marchandises dangereuses en cause. Le conseiller en service fournit des renseignements techniques sur les propriétés physiques, chimiques, toxicologiques et autres des produits; il recommande des mesures correctives à prendre en cas d'incendie, d'étanchement ou de fuite;  3, fiche 6, Français, - propri%C3%A9t%C3%A9%20toxicologique

Fiche 6,  Justifications,  Espagnol

Fiche 7,  Justifications,  Anglais

Record number: 7, Textual support number: 1 CONT

"hazard information" means information on the proper and safe storage, handling and use of a controlled product and includes information relating to its toxicological properties.  1, fiche 7, Anglais, - hazard%20information

Fiche 7,  Justifications,  Français

Record number: 7, Textual support number: 1 OBS

Loi sur les produits dangereux. Régl. concernant les produits contrôlés et Réglementation du Canada sur l'hygiène et la sécurité au travail.  1, fiche 7, Français, - renseignements%20sur%20les%20dangers

Fiche 7,  Justifications,  Espagnol