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Chromogranin B (secretogranin I or Scg-1) is a tyrosine-sulfated secretory protein found in a wide variety of peptidergic endocrine cells. Benedum et al. (1987) isolated a 2.5-kb cDNA clone from a cDNA library of human pheochromocytoma. Chromogranin B is a 657 amino acid long polypeptide of 76 kilodaltons and is preceded by a cleaved end-terminal signal peptide of 20 residues. Chromogranin B was assigned to chromosome 20 by Craig et al. (1986). Craig et al. (1987) showed by in situ hybridization that the CHGB locus is on 20pter-p12. Jenkins et al. (1991) mapped the murine gene, symbolized Scg-1, to chromosome 2 by in situ hybridization and by interspecific backcross analysis.  2, fiche 1, Anglais, - chromogranin%20B

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Record number: 1, Textual support number: 1 CONT

Le peptide correspondant à la séquence C-terminale de la chromogranine B a une activité lytique sélective contre la bactérie Micrococcus luteus à des concentrations infimes [...]  2, fiche 1, Français, - chromogranine%20B

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