TERMIUM Plus^®

Fiche 1,  Justifications,  Anglais

Record number: 1, Textual support number: 1 CONT

A knowledge of the fate of a drug, its disposition (absorption, distribution, metabolism, and excretion, known by the acronym ADME) and pharmacokinetics ... plays a central role throughout pharmaceutical research and development. These studies aid in the discovery and selection of new chemical entities, support safety assessment, and are critical in defining conditions for safe and effective use in patients. ADME studies provide [a] basis for critical judgments from situations where the behavior of the drug is understood to those where it is unknown: this is most important in bridging from animal studies to the human situation.  3, fiche 1, Anglais, - absorption%2C%20distribution%2C%20metabolism%20and%20excretion%20study

Fiche 1,  Justifications,  Français

Fiche 1,  Justifications,  Espagnol

Fiche 2,  Justifications,  Anglais

Record number: 2, Textual support number: 1 DEF

... the study of variability in the absorption, distribution, metabolism, and excretion (ADME) of a medicine between individuals (healthy volunteers or patients).  4, fiche 2, Anglais, - population%20pharmacokinetics

Fiche 2,  Justifications,  Français

Record number: 2, Textual support number: 1 DEF

[...] étude de la variabilité de l'absorption, de la distribution, du métabolisme et de l'excrétion(ADME) d’un médicament entre individus(volontaires sains ou patients).  1, fiche 2, Français, - pharmacocin%C3%A9tique%20de%20population

Record number: 2, Textual support number: 1 CONT

Afin de comprendre comment des individus d’une population diffèrent entre eux, il est nécessaire de procéder à une analyse de la pharmacocinétique des populations.  1, fiche 2, Français, - pharmacocin%C3%A9tique%20de%20population

Fiche 2,  Justifications,  Espagnol