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Fiche 1,  Justifications,  Anglais

Record number: 1, Textual support number: 1 DEF

The condition [or disease] that results when the immune cells of a transplant (usually of bone marrow) from a donor attack the tissues of the person receiving the transplant.  2, fiche 1, Anglais, - graft%20versus%20host%20disease

Record number: 1, Textual support number: 1 CONT

In 1955, Barnes and Loutit first described graft versus host disease (GVHD) in mice. Simonsen introduced the term graft-versus-host reaction in 1958 to describe the direction of the immunological damage caused by introduction of immunologically competent cells into an immunocompromised host. In 1966, Billingham proposed 3 conditions required for the development of GVHD, as follows: (1) the graft must contain immunologically competent cells, (2) the host must possess important transplant alloantigens that are lacking in the donor graft so that the host appears foreign to the graft, and (3) the host itself must be incapable of mounting an effective immunological reaction against the graft. According to the accepted definition, the immunologic assault itself and its consequences are referred to as GVHD.  3, fiche 1, Anglais, - graft%20versus%20host%20disease

Fiche 1,  Justifications,  Français

Record number: 1, Textual support number: 1 CONT

La principale complication, en cas d'allogreffe, est la maladie du greffon contre l'hôte. [...] Il s'agit d'une réaction immunitaire des cellules du greffon contre les organes du receveur. Cette réaction peut être aiguë, dans les trois premiers mois suivant la greffe, ou chronique et constituer une vraie maladie.  2, fiche 1, Français, - maladie%20du%20greffon%20contre%20l%27h%C3%B4te

Record number: 1, Textual support number: 1 OBS

Ne pas confondre avec : réaction du greffon contre l'hôte.  3, fiche 1, Français, - maladie%20du%20greffon%20contre%20l%27h%C3%B4te

Fiche 1,  Justifications,  Espagnol