TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
COVALENT MODIFICATION [1 record]
Record 1 - internal organization data 2010-12-23
Record 1, English
Record 1, Subject field(s)
- Biological Sciences
Record 1, Main entry term, English
- covalent modification
1, record 1, English, covalent%20modification
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Modification of enzymes, which is often, but not always, accomplished by the addition of a phosphate group to a specific serine, threonine, or tyrosine residue in the enzyme. The phosphate comes from ATP and its transfer is catalyzed by enzymes known as protein kinases ... Phosphorylation alters the shape of an enzyme in such a way as to increase or inhibit its activity. The subsequent removal of the phosphate group, which reverses the effect of the phosphorylation, is achieved by a second enzyme, called a phosphoprotein phosphatase. 1, record 1, English, - covalent%20modification
Record number: 1, Textual support number: 1 CONT
Nucleophilic catalysis is a specific example of covalent catalysis: the substrate is transiently modified by formation of a covalent bond with the catalyst to give a reactive intermediate. There are also many examples of electrophilic catalysis by covalent modification. 2, record 1, English, - covalent%20modification
Record 1, French
Record 1, Domaine(s)
- Sciences biologiques
Record 1, Main entry term, French
- modification covalente
1, record 1, French, modification%20covalente
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Modulation réversible de l'activité enzymatique par la fixation covalente et transitoire de certains composés chimiques. L'exemple historique est celui des enzymes responsables du métabolisme contrôlé du glycogène. En fait, il s'agit ici du type de contrôle que peuvent exercer certaines hormones, dont la noradrénaline, sur des activités enzymatiques. 2, record 1, French, - modification%20covalente
Record number: 1, Textual support number: 1 CONT
L'activité de nombreux enzymes est contrôlée, non pas par la formation de complexes entre enzymes et molécules régulatrices, mais par des modifications covalentes de l'enzyme. La plus connue de ces modifications est la phosphorylation/déphosphorylation des aminoacides hydroxylés; cette modification, catalysée dans un sens par une kinase, dans l'autre par une phosphatase, joue un rôle très important dans de nombreux mécanismes, comme par exemple la transmission de l'influx nerveux. [...] Un autre exemple de modification est [...] la transformation d'un proenzyme inactif en enzyme actif par coupure(s) protéolytique(s). 3, record 1, French, - modification%20covalente
Record 1, Spanish
Record 1, Textual support, Spanish
Copyright notice for the TERMIUM Plus® data bank
© Public Services and Procurement Canada, 2024
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau
Features
Language Portal of Canada
Access a collection of Canadian resources on all aspects of English and French, including quizzes.
Writing tools
The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.
Glossaries and vocabularies
Access Translation Bureau glossaries and vocabularies.
- Date Modified: