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2-DGE [1 record]
Record 1 - internal organization data 2003-04-30
Record 1, English
Record 1, Subject field(s)
- Genetics
- Molecular Biology
Record 1, Main entry term, English
- two-dimensional gel electrophoresis
1, record 1, English, two%2Ddimensional%20gel%20electrophoresis
correct
Record 1, Abbreviations, English
- 2-DGE 1, record 1, English, 2%2DDGE
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
One current proteomic tool for visualizing and quantitating all proteins expressed in a ological system at a given time is two-dimensional gel electrophoresis (2-DGE). As originally described by Patrick O'Farrell for analyzing Escherichia coli proteins in 1975, 2-DGE combines the electrophoretic separation of denatured proteins bysoelectric point charge differences in the first dimension with separation based on molecular size differences in the second dimension. The proteins, which can be detected using protein-specific stains, appear as constellations of spots in the 2-D space of the gel. Over the 20-year history of 2-DGE, numerous algorithms have been developed for comparing 2-DGE patterns and quantitatively analyzing protein abundance. 2, record 1, English, - two%2Ddimensional%20gel%20electrophoresis
Record 1, French
Record 1, Domaine(s)
- Génétique
- Biologie moléculaire
Record 1, Main entry term, French
- électrophorèse sur gel à deux dimensions
1, record 1, French, %C3%A9lectrophor%C3%A8se%20sur%20gel%20%C3%A0%20deux%20dimensions
correct, feminine noun
Record 1, Abbreviations, French
- 2-DGE 2, record 1, French, 2%2DDGE
correct, feminine noun
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Le deuxième souffle de la protéomique a aussi pour moteur l'automatisation et l'amélioration de la sensibilité de l'électrophorèse sur gel à deux dimensions (2-DGE), technique de séparation des protéines contenues dans les extraits cellulaires, les perfectionnements des méthodes de spectrométrie de masse qui permettent d'identifier une protéine et ses modifications [...]. 1, record 1, French, - %C3%A9lectrophor%C3%A8se%20sur%20gel%20%C3%A0%20deux%20dimensions
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
- Biología molecular
Record 1, Main entry term, Spanish
- electroforesis bidimensional en gel
1, record 1, Spanish, electroforesis%20bidimensional%20en%20gel
feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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