TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
PRINCIPALE CIBLE [7 records]
Record 1 - internal organization data 2024-02-19
Record 1, English
Record 1, Subject field(s)
- Pharmacology
Record 1, Main entry term, English
- pharmacological class
1, record 1, English, pharmacological%20class
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- pharmacologic class 2, record 1, English, pharmacologic%20class
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Drugs that share similar characteristics are grouped together as a pharmacologic class (or family). Beta-adrenergic blockers are an example of a pharmacologic class, because all the drugs in that class perform in the same way. 3, record 1, English, - pharmacological%20class
Record 1, French
Record 1, Domaine(s)
- Pharmacologie
Record 1, Main entry term, French
- classe pharmacologique
1, record 1, French, classe%20pharmacologique
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Ensemble des médicaments ayant la même cible et la même propriété pharmacodynamique principale. 1, record 1, French, - classe%20pharmacologique
Record number: 1, Textual support number: 1 OBS
Exemples : anticalciques, bêta-bloquants, antihistaminiques H2, bêta-stimulants, corticoïdes… 1, record 1, French, - classe%20pharmacologique
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2020-11-09
Record 2, English
Record 2, Subject field(s)
- Military Strategy
- Special-Language Phraseology
Record 2, Main entry term, English
- prime target
1, record 2, English, prime%20target
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- principal target 2, record 2, English, principal%20target
correct
Record 2, French
Record 2, Domaine(s)
- Stratégie militaire
- Phraséologie des langues de spécialité
Record 2, Main entry term, French
- principale cible
1, record 2, French, principale%20cible
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2020-05-07
Record 3, English
Record 3, Subject field(s)
- Animal Reproduction
- Animal Biology
Record 3, Main entry term, English
- inbreeding depression
1, record 3, English, inbreeding%20depression
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
A decreased vigor in terms of growth, survival, or fertility following one or more generations of inbreeding. 2, record 3, English, - inbreeding%20depression
Record 3, Key term(s)
- in-breeding depression
Record 3, French
Record 3, Domaine(s)
- Reproduction des animaux
- Biologie animale
Record 3, Main entry term, French
- dépression de consanguinité
1, record 3, French, d%C3%A9pression%20de%20consanguinit%C3%A9
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
- dépression endogamique 2, record 3, French, d%C3%A9pression%20endogamique
correct, feminine noun
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Généralement, quand on parle de consanguinité, on cible sa principale conséquence négative, désignée comme étant la dépression de consanguinité. 3, record 3, French, - d%C3%A9pression%20de%20consanguinit%C3%A9
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Reproducción de animales
- Biología animal
Record 3, Main entry term, Spanish
- depresión por consanguinidad
1, record 3, Spanish, depresi%C3%B3n%20por%20consanguinidad
correct, feminine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
- decaimiento endogámico 2, record 3, Spanish, decaimiento%20endog%C3%A1mico
feminine noun
- depresión endogámica 2, record 3, Spanish, depresi%C3%B3n%20endog%C3%A1mica
feminine noun
Record 3, Textual support, Spanish
Record 4 - internal organization data 2012-04-10
Record 4, English
Record 4, Subject field(s)
- General Vocabulary
Record 4, Main entry term, English
- main target
1, record 4, English, main%20target
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
The main target on the reduction in accidental fire deaths in the home is mandatory if the PSA target is to be met. If the overall reduction in deaths is not achieved then the target will not have been met, irrespective of progress towards the other aspects of the target. 2, record 4, English, - main%20target
Record 4, French
Record 4, Domaine(s)
- Vocabulaire général
Record 4, Main entry term, French
- cible principale
1, record 4, French, cible%20principale
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2010-04-20
Record 5, English
Record 5, Subject field(s)
- Biotechnology
- Genetics
Record 5, Main entry term, English
- basic myelin protein
1, record 5, English, basic%20myelin%20protein
correct
Record 5, Abbreviations, English
- BMP 2, record 5, English, BMP
correct
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study. A neurological surveillance was combined with prospective recording of upper respiratory and gastrointestinal infections and serological diagnosis of five common viral infections in 60 benign multiple sclerosis patients with a mean follow-up of 31 months... There was a significant correlation between adenovirus CF titre rises associated with upper respiratory tract infections and the occurrence of a major MS relapse in the AR period (n=7), while influenza infections were not followed by a major S relapse (n=6). Linear homologies have been demonstrated between adenovirus and basic myelin protein. The epidemiological approach is essential to our understanding of systemic antigens triggering multiple sclerosis activity. 3, record 5, English, - basic%20myelin%20protein
Record 5, French
Record 5, Domaine(s)
- Biotechnologie
- Génétique
Record 5, Main entry term, French
- protéine BMP
1, record 5, French, prot%C3%A9ine%20BMP
proposal, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Environ deux millions de personnes dans le monde sont atteintes par la sclérose en plaques, l'une des maladies auto-immunes les plus graves et les plus répandues. Elle est due à la destruction des gaines de myéline par des lymphocytes T dont la cible principale est une séquence de 14 acides aminés de la "basic myelin protein"(BMP), l'une des protéines constitutives de la gaine de myéline. 2, record 5, French, - prot%C3%A9ine%20BMP
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2004-10-05
Record 6, English
Record 6, Subject field(s)
- Biochemistry
- Microbiology and Parasitology
Record 6, Main entry term, English
- CD4 receptor
1, record 6, English, CD4%20receptor
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
- CD4 1, record 6, English, CD4
correct
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
CD4, symbol for a glycoprotein expressed on the surface of most thymocytes and some lymphocytes, including Helper T cells. Human CD4 is the receptor that serves as a docking site for HIV viruses on certain lymphocyte cells. Binding of the viral glycoprotein gp120 to CD4 is the first step in viral entry, leading to the fusion of viral and cell membranes. 1, record 6, English, - CD4%20receptor
Record 6, French
Record 6, Domaine(s)
- Biochimie
- Microbiologie et parasitologie
Record 6, Main entry term, French
- récepteur CD4
1, record 6, French, r%C3%A9cepteur%20CD4
correct, feminine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
- molécule CD4 2, record 6, French, mol%C3%A9cule%20CD4
correct, feminine noun
Record 6, Textual support, French
Record number: 6, Textual support number: 1 OBS
Le VIH infecte principalement les cellules qui possèdent le récepteur CD4 se servant de ce dernier pour pénétrer à l'intérieur du génome. Les lymphocytes T sont la principale cible du virus quoique les macrophages, les cellules dendritiques de Langerhans, les cellules de la microglie du cerveau et les cellules épithéliales du système digestif servent également de porte d’entrée au virus. 1, record 6, French, - r%C3%A9cepteur%20CD4
Record number: 6, Textual support number: 1 CONT
La fixation du V.I.H. à la cellule CD4+. La fixation de la particule virale sur la cible cellulaire se fait par interaction de la gp120 et de la molécule CD4, ce qui découvre la glycioritéine transmembranaire gp41. Une des extrémités de la gp41 s’introduit alors dans la membrane cellulaire et cet accrochage engendre la fusion entre la membrane virale et la membrane cellulaire. Le mécanisme de la pénétration intracellulaire du V.I.H. reste encore discuté. L’enveloppe virale conditionne donc l’infectivité du V.I.H. puisqu’il s’attache spécifiquement à la cellule qu’il infecte par l’intermédiaire de ses glycoprotéines d’enveloppe. Pour certains, la molécule CD4 n’interviendrait pas cependant comme un récepteur fonctionnel du V.I.H. Après la liaison spécifique de la gp120 à la molécule CD4 à la surface cellulaire, le virus pénétre dans la cellule. Libéré de son enveloppe, sa capside est détruite et l’ARN du génome transcrit en ADN par la transcriptase inverse. 2, record 6, French, - r%C3%A9cepteur%20CD4
Record 6, Spanish
Record 6, Campo(s) temático(s)
- Bioquímica
- Microbiología y parasitología
Record 6, Main entry term, Spanish
- receptor CD4
1, record 6, Spanish, receptor%20CD4
correct, masculine noun
Record 6, Abbreviations, Spanish
Record 6, Synonyms, Spanish
Record 6, Textual support, Spanish
Record number: 6, Textual support number: 1 OBS
Las células T4 son leucocitos, es decir glóbulos blancos. Un subgrupo de ellos, que tiene en su superficie una molécula llamada CD4, coincide con la forma de la proteína GP-120 del virus, razón por la cual éste se une específicamente al linfocito T4, debido a la gran afinidad que tiene a esta célula, llamada también célula CD4 por el nombre del receptor. 1, record 6, Spanish, - receptor%20CD4
Record 7 - internal organization data 1996-06-02
Record 7, English
Record 7, Subject field(s)
- International Relations
- Phraseology
Record 7, Main entry term, English
- big enchilada 1, record 7, English, big%20enchilada
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record 7, French
Record 7, Domaine(s)
- Relations internationales
- Phraséologie
Record 7, Main entry term, French
- l’homme au sommet
1, record 7, French, l%26rsquo%3Bhomme%20au%20sommet
masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
- la principale cible 1, record 7, French, la%20principale%20cible
feminine noun
Record 7, Textual support, French
Record number: 7, Textual support number: 1 OBS
Vocabulaire datant du scandale du Watergate. Expression encore employée. 1, record 7, French, - l%26rsquo%3Bhomme%20au%20sommet
Record 7, Spanish
Record 7, Textual support, Spanish
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