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ALL-TRANS RETINOIC ACID [1 record]

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Record 1 1991-07-09

English

Subject field(s)
  • Biochemistry
CONT

Acute promyelocytic leukemia is a rare and severe leukemia ... All-trans retinoic acid, a vitamin A derivative, is able to induce complete remission via a differentiation effect in almost all cases of first attack (Chinese and French results) or in first relapse (French data).

OBS

Tiré de: Blood 1990; 76; 1704-9.

French

Domaine(s)
  • Biochimie
CONT

La leucémie aiguë promyélocytaire est une leucémie rare, grave, une urgence thérapeutique en raison du syndrome de coagulation intravasculaire disséminée (CIVD). Cette leucémie est associée à une anomalie cytogénétique, la translocation t(15 ; 17). L'acide tout-trans rétinoïque est capable, dans la majorité des cas, au moment du diagnostic ou lors de la première rechute, d'induire une rémission complète par différenciation de la cellule maligne.

Spanish

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