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ALLELE-SPECIFIC OLIGONUCLEOTIDE [1 record]

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Record 1 2024-08-12

English

Subject field(s)
  • Genetics

French

Domaine(s)
  • Génétique
CONT

En utilisant la technique d'amplification par PCR [réaction en chaîne de la polymérase] et le typage moléculaire à l'aide d'oligonucléotides spécifiques d'allèles, nous avons étudié le polymorphisme des gènes HLA [antigène leucocytaire humain (de l'anglais Human Leukocyte Antigen)] de classe II en relation avec deux maladies auto-immunes : le diabète insulino-dépendant et la myasthénie grave.

Spanish

Campo(s) temático(s)
  • Genética
CONT

El oligonucleótido específico de alelo es una técnica que permite la detección de mutaciones de una sola base sin necesidad de PCR [reacción en cadena de la polimerasa] o electroforesis en gel.

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