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ALLOSTERIC SITE [1 record]
Record 1 - internal organization data 2003-11-10
Record 1, English
Record 1, Subject field(s)
- Biological Sciences
Record 1, Main entry term, English
- allosteric site
1, record 1, English, allosteric%20site
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A topologically separate site of an enzyme which lacks catalytic activity but which can exert regulatory control over the active site. 2, record 1, English, - allosteric%20site
Record 1, French
Record 1, Domaine(s)
- Sciences biologiques
Record 1, Main entry term, French
- site allostérique
1, record 1, French, site%20allost%C3%A9rique
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- site régulateur 2, record 1, French, site%20r%C3%A9gulateur
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les enzymes allostériques possèdent deux types de site: le site actif qui se combine au substrat et qui catalyse la réaction enzymatique, les sites régulateurs qui peuvent se combiner à un effecteur, soit activateur, soit inhibiteur. Les deux types de site sont séparés sur la molécule. Dans certaines enzymes ils appartiennent même à des chaînes polypeptidiques différentes. La désensibilisation de l'enzyme résulte de l'inactivation des sites régulateurs. [...] Lorsqu'un inhibiteur allostérique se fixe au site allostérique, il se produit aussi une transition allostérique (également réversible), entraînant une modification au niveau du site actif, qui cette fois prend une conformation moins favorable à la fixation du substrat. 3, record 1, French, - site%20allost%C3%A9rique
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Ciencias biológicas
Record 1, Main entry term, Spanish
- sitio alostérico
1, record 1, Spanish, sitio%20alost%C3%A9rico
masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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