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FACTEUR ANGIOGENIQUE [1 record]

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Record 1 1991-07-15

English

Subject field(s)
  • Cytology
CONT

Because of the prominent noevascularization observed in the growth of brain tumors, we studies the occurrence of basic fibroblast growth factor (bFGF) a potent angiogenic factor in astrocytomas, the most aggressive of which often have marked vascular hyperplasia. Using immunohistochemical methods, we examined 21 examples of such tumors, 7 glioblastomas multiform, 7 anaplastic astrocytomas, and 7 low grade astrocytomas. Results suggest a possible role for bFGF in tumor growth and in angiogenesis in astrocytomes.

OBS

Tiré du périodique: Cancer Research, 1990, 50 (22), 7393-7398.

French

Domaine(s)
  • Cytologie
CONT

De nombreux facteurs de croissance sont susceptibles d'induire une angiogénèse in vitro et/ou in vivo. Plusieurs d'entre eux ont pu être purifiés, séquencés et clonés. (...) Nous limiterons cette revue à certains facteurs angiogéniques (...).

OBS

Parmi les facteurs angiogéniques, on distingue l'angiotropine, la vasculotropine, le TGF (transforming growth factor), la thombine alpha, le TNF alpha et le "tumor vascular permeability factor".

Spanish

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