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FACTEUR WINGLESS/WNT1 [1 record]

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Record 1 1997-02-26

English

Subject field(s)
  • Genetics

French

Domaine(s)
  • Génétique
CONT

[...] le système de transmission du signal Hedgehog est à l'honneur. Son régulateur négatif, Patched, est déficient dans le syndrome de Gorlin et des épithéliomas baso-cellulaires sporadiques. L'une des cibles du signal Hedgehog est le facteur Wingless/Wnt1, lui même impliqué dans la régulation de la prolifération et de la morphogénèse. Ce facteur agit en contrôlant la quantité et l'activité de la ß-caténine [...].

Spanish

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