TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
HUMAN RECOMBINANT DNASE [1 record]
Record 1 - internal organization data 2008-11-21
Record 1, English
Record 1, Subject field(s)
- Molecular Biology
Record 1, Main entry term, English
- recombinant human deoxyribonuclease
1, record 1, English, recombinant%20human%20deoxyribonuclease
correct
Record 1, Abbreviations, English
- rhDNase 1, record 1, English, rhDNase
correct
Record 1, Synonyms, English
- human recombinant DNase 2, record 1, English, human%20recombinant%20DNase
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Fibrinolytic enzymes, particularly streptokinase, are now widely used to treat empyema thoracis. Recent in vitro evidence suggests that streptokinase has no effect on pus viscosity but that deoxyribonuclease (DNase) reduces the viscosity of pus. We report the first use of human recombinant DNase given intrapleurally to treat an empyema which had not resolved after standard treatment with streptokinase. 2, record 1, English, - recombinant%20human%20deoxyribonuclease
Record number: 1, Textual support number: 2 CONT
There have been no controlled studies to test the efficacy of tissue plasminogen activator (tPA) or recombinant human deoxyribonuclease (rhDNase) in the treatment of empyema. In vitro studies show that streptokinase without rhDNase does not liquefy empyemic material from rabbits. However, the combination of streptokinase and streptodornase and rhDNase have been shown to liquefy pus in vitro. 1, record 1, English, - recombinant%20human%20deoxyribonuclease
Record 1, French
Record 1, Domaine(s)
- Biologie moléculaire
Record 1, Main entry term, French
- DNase recombinante humaine
1, record 1, French, DNase%20recombinante%20humaine
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- désoxyribonucléase recombinante humaine 2, record 1, French, d%C3%A9soxyribonucl%C3%A9ase%20recombinante%20humaine
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Le traitement par pulvérisation de DNase recombinante humaine (dornase alpha), à la dose de 2,5 mg une fois par jour, entraîne une augmentation légère mais significative de la fonction pulmonaire (environ 6%) chez les patients dont l'atteinte pulmonaire est modérément sévère. 1, record 1, French, - DNase%20recombinante%20humaine
Record number: 1, Textual support number: 2 CONT
La dornase alfa (Pulmozyme®) est une désoxyribonucléase recombinante humaine, similaire à l'enzyme humaine qui hydrolyse l'ADN extracellulaire. Elle diminue la viscosité du mucus et fluidifie les sécrétions bronchiques des patients atteints de mucoviscidose. 2, record 1, French, - DNase%20recombinante%20humaine
Record 1, Spanish
Record 1, Textual support, Spanish
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