TERMIUM Plus®

From: Translation Bureau

On social media

Consult the Government of Canada’s terminology data bank.

TOLERANCE PHARMACODYNAMIQUE [1 record]

Record 1 2023-06-01

English

Subject field(s)
  • Pharmacodynamics
  • Drugs and Drug Addiction
  • Toxicology
CONT

Pharmacodynamic tolerance ... results from changes in the drug–receptor interaction. These changes may involve a decrease in the number of receptors or a change in the signal transduction pathway ... In the short term, changes in receptor number or binding affinity can be caused by inactivation or receptors ..., internalization, and degradation of cell surface receptors, or other mechanisms.

French

Domaine(s)
  • Pharmacodynamie
  • Drogues et toxicomanie
  • Toxicologie
CONT

[...] lors d'un traitement prolongé par des opiacés, la tolérance analgésique peut être due à une évolution de la pathologie, à une modification du métabolisme (tolérance pharmacocinétique) ou encore à une modification du signal opioïdergique (tolérance pharmacodynamique).

Spanish

Campo(s) temático(s)
  • Farmacodinámica
  • Drogas y toxicomanía
  • Toxicología
Save record 1

Copyright notice for the TERMIUM Plus® data bank

© Public Services and Procurement Canada, 2026
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau

Features

GCtranslate (available on the Government of Canada network only)

Use this artificial intelligence prototype to translate Government of Canada content up to and including Protected B. Available to employees of selected departments and agencies only.

Writing tools

The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.

Glossaries and vocabularies

Access Translation Bureau glossaries and vocabularies.

Date Modified: