TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

CASCADE UNIT [2 records]

Record 1 2014-12-17

English

Subject field(s)
  • Nuclear Science and Technology
  • Atomic Physics
OBS

Base material fed into a cascade or separation unit for separation into an enriched fraction of the material.

OBS

feed: term and definition standardized by ISO in 1997.

French

Domaine(s)
  • Sciences et techniques nucléaires
  • Physique atomique
OBS

Matière de base introduite dans une cascade ou une unité de séparation en vue d'être séparée en une fraction enrichie et une fraction appauvrie.

OBS

alimentation : terme et définition normalisés par l'ISO en 1997.

Spanish

Save record 1

Record 2 1997-05-07

English

Subject field(s)
  • Genetics
  • Molecular Biology
CONT

A very original set of experiments carried out by the Unit of Molecular Biology of Gene Expression concerns another protein essential for mouse development that is also a transcription factor. This factor known as KBF2 or RBP-Jk is homologous to a Drosophila gene product, Su(H)(Suppressor of Hairless), which belongs to the Notch signal transduction cascade involved in regulating the competence of a cell to respond to specific developmental cues. A likely function of the Su(H) protein is to serve as an anchor on DNA for non DNA-binding transcriptional activators. This function is conserved in the Notch pathway : the activation of this transmembrane receptor likely involves a proteolytic cleavage step which releases its intracellular domain; following nuclear translocation, it activates its target genes by binding to the Su(H) protein, which is already bound to several sites in the target promoters.

French

Domaine(s)
  • Génétique
  • Biologie moléculaire
CONT

La protéine Su(H), impliquée dans l'activité de transmission de ce signal, semble capable de s'associer à la région intracellulaire de Notch. C'est un facteur de transcription qui se lie à certaines séquences localisées dans les promoteurs de plusieurs des gènes cibles de Notch.

Spanish

Save record 2

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