TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
CD8 [7 records]
Record 1 - internal organization data 2014-10-29
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- immunopeptidome
1, record 1, English, immunopeptidome
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Self/non-self discrimination is a fundamental requirement of life. Endogenous peptides presented by major histocompatibility complex class I(MHC I) molecules represent the essence of self for CD8 T lymphocytes. These MHC I peptides(MIPs) are collectively referred to as the immunopeptidome. 2, record 1, English, - immunopeptidome
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- immunopeptidome
1, record 1, French, immunopeptidome
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La différentiation entre le «soi» et le «non-soi» est un processus biologique essentiel à la vie. Les peptides endogènes présentés par les complexes majeurs d’histocompatibilité de classe I (CMH I) représentent le fondement du «soi» pour les lymphocytes T CD8+. On donne le nom d’immunopeptidome à l’ensemble des peptides présentés à la surface cellulaire par les molécules du CMH I. 2, record 1, French, - immunopeptidome
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2004-10-05
Record 2, English
Record 2, Subject field(s)
- Immunology
Record 2, Main entry term, English
- helper/suppressor ratio
1, record 2, English, helper%2Fsuppressor%20ratio
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- CD4/CD8 1, record 2, English, CD4%2FCD8
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
Abnormalities in numbers of CD4+ and CD8+ T-cell subsets and the helper/suppressor ratio(CD4/CD8) were used very early in the AIDS epidemic to help define persons affected with AIDS before a screening test for HIV-1 was available. A low number of CD4+ lymphocytes alone or in combination with a decreased CD4 :CD8 ratio and total lymphocyte count can be useful as a predictor of HIV-1 seropositivity and progression of disease. 1, record 2, English, - helper%2Fsuppressor%20ratio
Record 2, Key term(s)
- T8/T4 ratio
Record 2, French
Record 2, Domaine(s)
- Immunologie
Record 2, Main entry term, French
- rapport CD4/CD8
1, record 2, French, rapport%20CD4%2FCD8
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Les CD4 ou T4 sont une sorte de globules blancs, des lymphocytes qui jouent un rôle capital dans le déclenchement d'une réaction immunitaire (de défense du corps) face à un "envahisseur". Ils sont aussi la cible privilégiée des VIH. [...] On utilise parfois [...] comme indicateur le rapport CD4/CD8, ces derniers étant les éléments qui assurent la clôture d'une réaction immunitaire. 1, record 2, French, - rapport%20CD4%2FCD8
Record 2, Key term(s)
- rapport T4/T8
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Inmunología
Record 2, Main entry term, Spanish
- relación CD4/CD8
1, record 2, Spanish, relaci%C3%B3n%20CD4%2FCD8
feminine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 DEF
Correspondencia cuantitativa que se establece entre las células CD4 cooperadoras y las CD8 supresoras. 1, record 2, Spanish, - relaci%C3%B3n%20CD4%2FCD8
Record number: 2, Textual support number: 1 OBS
En condiciones normales, [la relación CD4/CD8] debe ser por arriba de uno, aproximadamente 2:1. En la mayoría de los casos de VIH, esta relación se encuentra invertida y es menor de uno. 1, record 2, Spanish, - relaci%C3%B3n%20CD4%2FCD8
Record 3 - internal organization data 2004-10-05
Record 3, English
Record 3, Subject field(s)
- Immunology
Record 3, Main entry term, English
- CD8
1, record 3, English, CD8
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
One type of function-determining membrane glycoprotein exists in two forms called T4 or T8(CD4 or CD8 in another system of nomenclature) ;T4 molecules are on helper T cells, T8 molecules are on suppressor and cytotoxic T cells. 1, record 3, English, - CD8
Record 3, French
Record 3, Domaine(s)
- Immunologie
Record 3, Main entry term, French
- CD8
1, record 3, French, CD8
correct, see observation, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
- T8 1, record 3, French, T8
masculine noun
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Protéine de surface caractéristique des lymphocytes T8. 1, record 3, French, - CD8
Record number: 3, Textual support number: 1 OBS
On emploie souvent ce terme pour désigner les lymphocytes T8. 1, record 3, French, - CD8
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Inmunología
Record 3, Main entry term, Spanish
- célula CD8
1, record 3, Spanish, c%C3%A9lula%20CD8
feminine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
- T8 citotóxica 1, record 3, Spanish, T8%20citot%C3%B3xica
feminine noun
- célula T8 supresora 1, record 3, Spanish, c%C3%A9lula%20T8%20supresora
feminine noun
Record 3, Textual support, Spanish
Record number: 3, Textual support number: 1 OBS
Célula [que] tiene la molécula CD8 en su membrana externa y que tiene por función inhibir la respuesta inmune. 1, record 3, Spanish, - c%C3%A9lula%20CD8
Record 4 - internal organization data 2000-05-17
Record 4, English
Record 4, Subject field(s)
- Immunology
- Cytology
Record 4, Main entry term, English
- cytotoxic T lymphocyte precursor
1, record 4, English, cytotoxic%20T%20lymphocyte%20precursor
correct
Record 4, Abbreviations, English
- CTLp 2, record 4, English, CTLp
correct
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
The development of influenza virus-specific CD8+ cytotoxic T lymphocyte precursors(CTLp) is diminished in H-2b mice that are homozygous(-/-) for disruption of the H-2IA b gene. Virus clearance was not obviously delayed when compared with the congenic H-2IAb(+/+) controls, and evidence of CTL activity was apparent for inflammatory cells recovered from the respiratory tract in both cases. However, the virus-specific CTLp that are normally present in the regional lymph nodes and in the infected lung were evidently being consumed at the peak of the host response to give the terminally differentiated CTL effectors. 1, record 4, English, - cytotoxic%20T%20lymphocyte%20precursor
Record 4, French
Record 4, Domaine(s)
- Immunologie
- Cytologie
Record 4, Main entry term, French
- précurseur de lymphocytes T cytotoxiques
1, record 4, French, pr%C3%A9curseur%20de%20lymphocytes%20T%20cytotoxiques
correct, masculine noun
Record 4, Abbreviations, French
- CTLp 2, record 4, French, CTLp
correct, masculine noun
Record 4, Synonyms, French
Record 4, Textual support, French
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 1993-03-24
Record 5, English
Record 5, Subject field(s)
- Immunology
Record 5, Main entry term, English
- CD4 molecule 1, record 5, English, CD4%20molecule
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
Recent studies have shown that the CD4 molecule does indeed have a weak affinity for MHC class II molecules. These observations support the idea that antigen recognition by T cells involves the formation of a complex of T cell antigen receptor and CD4 or CD8 on the T cell which recognizes antigen plus MHC on another cell. 1, record 5, English, - CD4%20molecule
Record 5, French
Record 5, Domaine(s)
- Immunologie
Record 5, Main entry term, French
- molécule CD4
1, record 5, French, mol%C3%A9cule%20CD4
feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
CD4 et CD8. Les cellules T matures des organes lymphoïdes périphériques expriment l'une ou l'autre de ces deux glycoprotéines, qui déterminent la classe de molécules de CMH reconnue en association avec l'antigène : classe II pour CD4 et classe I pour CD8. De poids moléculaires respectifs de 55 kDA et 32 kDA, elles appartiennent à la superfamille des immunoglobulines. Leur rôle est incertain : augmentation de l'avidité des récepteurs [bêta] ayant une faible avidité initiale, interaction avec les molécules de CMH, activation cellulaire. 1, record 5, French, - mol%C3%A9cule%20CD4
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 1993-03-24
Record 6, English
Record 6, Subject field(s)
- Lymphatic System
Record 6, Main entry term, English
- CD8 molecule 1, record 6, English, CD8%20molecule
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
Recent studies have shown that the CD4 molecule does indeed have a weak affinity for MHC class II molecules. These observations support the idea that antigen recognition by T cells involves the formation of a complex of T cell antigen receptor and CD4 or CD8 on the T cell which recognizes antigen plus MHC on another cell. 1, record 6, English, - CD8%20molecule
Record 6, French
Record 6, Domaine(s)
- Système lymphatique
Record 6, Main entry term, French
- molécule CD8
1, record 6, French, mol%C3%A9cule%20CD8
feminine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
CD4 et CD8. Les cellules T matures des organes lymphoïdes périphériques expriment l'une ou l'autre de ces deux glycoprotéines, qui déterminent la classe de molécules de CMH reconnue en association avec l'antigène : classe II pour CD4 et classe I pour CD8. De poids moléculaires respectifs de 55 kDA et 32 kDA, elles appartiennent à la superfamille des immunoglobulines. Leur rôle est incertain : augmentation de l'avidité des récepteurs [alpha][bêta] ayant une faible avidité initiale, interaction avec les molécules de CMH, activation cellulaire? 1, record 6, French, - mol%C3%A9cule%20CD8
Record 6, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 1993-03-22
Record 7, English
Record 7, Subject field(s)
- Immunology
Record 7, Main entry term, English
- T8 cell surface marker 1, record 7, English, T8%20cell%20surface%20marker
Record 7, Abbreviations, English
Record 7, Synonyms, English
- CD8 T cell surface marker 1, record 7, English, CD8%20T%20cell%20surface%20marker
Record 7, Textual support, English
Record number: 7, Textual support number: 1 CONT
T(OKT) antigens are human T cell surface markers.... T8(CD8) is present on cytotoxic and suppressor T cells and is involved in MHC class 1 restricted interactions. 1, record 7, English, - T8%20cell%20surface%20marker
Record 7, French
Record 7, Domaine(s)
- Immunologie
Record 7, Main entry term, French
- récepteur T8
1, record 7, French, r%C3%A9cepteur%20T8
masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
- récepteur CD8 1, record 7, French, r%C3%A9cepteur%20CD8
masculine noun
Record 7, Textual support, French
Record number: 7, Textual support number: 1 DEF
Récepteur des molécules de la classe I du complexe majeur d'histocompatibilité (présent à la surface des lymphocytes T). 1, record 7, French, - r%C3%A9cepteur%20T8
Record 7, Spanish
Record 7, Textual support, Spanish
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