TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

Addition of bacterial sphingomyelinase to quiescent Swiss 3T3 cells effectively potentiated the platelet-derived growth factor(PDGF)-stimulated cell proliferation, though the enzyme by itself had little effect on the cell proliferation. Such potentiation of the cell growth could also be observed by the addition of ceramide, a product of the sphingomyelinase-catalysed reaction. In contrast, phosphocholine, another product of the enzyme reaction, had no synergistic effect on the action of PDGF. Treatment of the cells with sphingomyelinase or ceramide increased the cellular activity of mitogen-activated protein kinases(MAP kinases), which have been implicated in the regulation of cell proliferation.  1, record 1, English, - sphingomyelinase

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 CONT

Certaines cytokines, des agents différentiateurs, ou des effecteurs antitumoraux activent une voie de transmission du signal intracellulaire caractérisée par l'hydrolyse de la sphingomyéline et production de céramide sous l'effet de sphingomyélinases.  1, record 1, French, - sphingomy%C3%A9linase

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

The stress-activated protein kinases(SAPKs), which are distantly related to the MAP kinases, are the dominant c-Jun amino-terminal protein kinases activated in response to a variety of cellular stresses, including treatment with tumour-necrosis factor-alpha and interleukin-beta[...] We have now identified a novel protein kinase, called SAPK/ERK kinase-1(SEK1), which is structurally related to the MAP kinase kinases(MEKs). SEK1 is a potent activator of the SAPKs in vitro and in vivo.  3, record 2, English, - SAPK%2FERK%20kinase%2D1

Record number: 2, Textual support number: 1 OBS

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Excerpt from Nature 372, 794-8, 1994.  4, record 2, English, - SAPK%2FERK%20kinase%2D1

Record 2,  Textual support,  French

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

An elemental computing device that occupies cells on a physical map and acts independently based on a small set of internal rules. Cellular automata : a new method for battlefield simulation.  1, record 3, English, - cellular%20automaton

Record 3,  Textual support,  French

Record 3,  Textual support,  Spanish