TERMIUM Plus®

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CELLULAR ONCOGENE [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2012-07-31

English

Subject field(s)
  • Cytology
  • Genetics
DEF

A proto-oncogene that has been activated within the host so that oncogenicity results.

OBS

proto-oncogene : a normal cellular gene that with alteration, such as by mutation, DNA rearrangement, or nearby insertion of viral DNA, becomes an active oncogene; most proto-oncogenes are believed to normally function in cell growth and differentiation.

Key term(s)
  • c onc

French

Domaine(s)
  • Cytologie
  • Génétique
CONT

Les oncogènes cellulaires (c-onc) correspondent à la version mutée de gènes intervenant dans de nombreuses fonctions normales de la cellule, et les oncogènes viraux (v-onc) sont constitués par des gènes cellulaires qui ont été jadis empruntés par les rétrovirus.

Key term(s)
  • c onc

Spanish

Campo(s) temático(s)
  • Citología
  • Genética
Save record 1

Record 2 2010-10-28

English

Subject field(s)
  • Biochemistry
CONT

Tyrosine kinase oncogenes and growth-regulatory signal transduction. Research in our laboratory is focused on the molecular mechanisms regulating cellular growth and differentiation in both normal and tumor cells. Using hematopoietic differentiation and fibroblast transformation as model systems, we are investigating the roles of non-receptor protein-tyrosine kinases and small G-proteins in these processes. Tyrosine kinase activity is associated with many proteins involved in growth-regulatory signal transduction, including growth hormone receptors and transforming oncogene products.

French

Domaine(s)
  • Biochimie
CONT

Les petites protéines G de la famille Rho (sous-groupe de la vaste famille Ras) jouent ainsi un rôle déterminant dans le contrôle de la réorganisation du cytosquelette d'actine. Elles agissent les unes sur les autres, en cascade, et collaborent avec de nombreux partenaires auxquels elles se lient par des domaines protéiques conservés, en un système dont nous avons déjà souligné la complexité.

Spanish

Campo(s) temático(s)
  • Bioquímica
CONT

Una clase principal de proteína G, denominada proteínas G pequeñas, es la familia ras, que fueron inicialmente identificadas como los productos de oncogenes de virus de sarcoma de rata.

Save record 2

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