TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

During replication a trinucleotide repeat sequence can either expand or contract; if expanded beyond a critical copy number, gene function is compromised. Triplet repeat expansion is now recognized as a cause of several human diseases and as a mechanism of inheritance to explain the phenomenon of anticipation.  2, record 1, English, - triplet%20repeat%20expansion

Record 1,  Textual support,  French

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Repetición de una secuencia de tres pares de bases nitrogenadas, como la repetición CAG responsable del síndrome del cromosoma X-frágil, que va aumentando el número de copias a lo largo de varias generaciones.  1, record 1, Spanish, - expansi%C3%B3n%20de%20triplete%20repetido

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

A mechanism within a target of evaluation whose failure would create a security weakness.  2, record 2, English, - critical%20mechanism

Record number: 2, Textual support number: 1 OBS

critical mechanism : designation used in Information Technology Security Evaluation Criteria(ITSEC).  3, record 2, English, - critical%20mechanism

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Mécanisme interne d'une cible d'évaluation qui n'est pas protégé par d'autres mécanismes et dont la défaillance créerait une vulnérabilité. [Définition reproduite avec l'autorisation de l'AFNOR.]  1, record 2, French, - m%C3%A9canisme%20critique

Record number: 2, Textual support number: 1 OBS

mécanisme critique : désignation utilisée dans le cadre des Critères d'évaluation de la sécurité des technologies de l'information (ITSEC).  2, record 2, French, - m%C3%A9canisme%20critique

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 OBS

Health Canada. The mandate of the EAC-VHP is to provide HPFB with on-going external expert broad strategic policy advice on the safety and therapeutic effectiveness of marketed health products for human use. It will also provide a mechanism to involve the public providing them with a forum to have their views heard by experts who can discuss their input and incorporate it into the advice provided. Incorporating the views of citizens and stakeholders is critical for effective regulation in the public interest.  1, record 3, English, - Expert%20Advisory%20Committee%20on%20the%20Vigilance%20of%20Health%20Products

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 OBS

Santé Canada. Le CCE-VPS a pour mandat de fournir, sur une base permanente, à la DGPSA de Santé Canada, des avis généraux d'experts de l'extérieur au sujet des politiques et des stratégies concernant l'innocuité et l'efficacité thérapeutique des produits de santé commercialisés à l'usage des humain. En plus, le Comité constituera un mécanisme permettant aux membres du public de participer à un forum afin de faire connaître leurs points de vue aux experts qui pourront par la suite les examiner et les incorporer dans les avis qu'ils seront appelés à fournir. L'intégration des points de vue des citoyens et des intervenants est essentielle pour assurer une réglementation efficace dans l'intérêt du public.  1, record 3, French, - Comit%C3%A9%20consultatif%20d%27experts%20sur%20la%20vigilance%20des%20produits%20de%20sant%C3%A9

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

A mechanism for identifying the new critical technologies required by specific sectors to meet future market demands.  3, record 4, English, - technology%20roadmap

Record number: 4, Textual support number: 1 CONT

[Industry Canada] facilitated six industry - led technology roadmaps by increasing awareness and understanding of the private sector ...  3, record 4, English, - technology%20roadmap

Record number: 4, Textual support number: 1 OBS

technology roadmap; TRM: term and abbreviation used at the Treasury Board Secretariat.  4, record 4, English, - technology%20roadmap

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Mécanisme qui permet de définir les nouvelles technologies déterminantes dont certains secteurs auront besoin pour répondre aux exigences du marché de demain.  5, record 4, French, - carte%20routi%C3%A8re%20technologique

Record number: 4, Textual support number: 1 CONT

[Industrie Canada] a contribué aux travaux ayant abouti à l'établissement de six cartes routières technologiques, sous la gouverne de l'industrie [...]  5, record 4, French, - carte%20routi%C3%A8re%20technologique

Record number: 4, Textual support number: 1 OBS

carte routière technologique; CRT; feuille de route technologique : termes et abréviation en usage au Secrétariat du Conseil du Trésor.  6, record 4, French, - carte%20routi%C3%A8re%20technologique

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

A chemically related group of drugs used to inhibit HIV. Examples include the first drugs approved to treat HIV infection : AZT, ddI, ddC. They all work by the same mechanism, by inhibiting an enzyme called reverse transcriptase that is critical for HIV's survival.  2, record 5, English, - nucleoside%20analogue

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Médicaments de la première famille historique des antirétroviraux, les inhibiteurs de la reverse-transcriptase (AZT, ddC, ddI, d4T, 3TC) à ce jour.  2, record 5, French, - analogue%20de%20nucl%C3%A9oside

Record 5,  Textual support,  Spanish

Record number: 5, Textual support number: 1 DEF

Compuesto sintético, que carece del grupo fosfatado que tienen los nucleótidos, que actúa como una versión defectuosa del nucleósido natural al inhibir la transcriptasa inversa, la cual es la enzima viral encargada de integrar estas cadenas transcribiendo el código ARN viral al ADN.  1, record 5, Spanish, - nucle%C3%B3sido%20an%C3%A1logo

Record number: 5, Textual support number: 1 OBS

El VIH utiliza al nucleósido para integrarlo a la cadena de ADN de la célula cuando trata de reproducirse. Al ser sustituido el nucleósido natural por el nucleósido análogo, la cadena no puede sintetizarse eficazmente y la replicación no se efectúa. Son nucleósidos análogos el AZT, ddI, ddC, d4T y 3TC.  1, record 5, Spanish, - nucle%C3%B3sido%20an%C3%A1logo

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 CONT

Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special proteins "aquaporins". Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues.  2, record 6, English, - aquaporin

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

Dans 90% des cas, le diabète insipide néphrogénique héréditaire lié à l'X, est dû à des mutations du récepteur de l'argénine-vasopressine qui affectent la première étape de la transmission du signal aboutissant au transport de l'eau. Dans 10% des cas, la maladie est liée à des mutations du gène de l'aquaporine.  1, record 6, French, - aquaporine

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

Optical Head(OH). The OH is typically located outside the spacecraft and performs the critical functions of generating and pointing the transmit laser beam and acquiring and tracking the received beacon and receive laser beams. Major elements of the OH are :-Coarse pointing assembly used for steering the terminal line of sight.-Optical subsystem comprising telescope, optical bench and beacon collimator.-Fine pointing assembly(FPA) : This is a mechanism used in conjunction with the tracking sensor to provide the tracking function for the terminal.-Point ahead assembly(PAA) : This is similar to the FPA and is used to introduce the required point ahead offset to the transmit beam.-Acquisition sensor(AS) : This is a wide field of view sensor used during acquisition for the identification and location of the partner terminal.-Tracking sensor(TS) : This is a fast sensor that operates in a closed loop with the FPA.  2, record 7, English, - point%2Dahead%20assembly

Record 7,  Textual support,  French

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

Two cellular mechanisms are hypothesized for associative changes in synaptic strength during learning. The pre-post coincidence mechanism, proposed by Donald O. Hebb in 1949, points that coincident activity in the presynaptic and postsynaptic neurons is critical for strengthening the connections between them. The premodulatory coincidence mechanism proposed in 1963, based on studies on the nervous system of the marine snail Aplysia, holds that the connection can be strengthened without activity of the postsynaptic cell when a third neuron, the modulatory neuron, is active at the same time as the presynaptic neuron.  1, record 8, English, - pre%2Dmodulatory%20coincidence%20mechanism

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

Deux mécanismes cellulaires pourraient expliquer les changements associatifs de la force des synapses au cours de l'apprentissage. Dans le mécanisme de coïncidence pré-post, proposé par Donald Hebb en 1949, l'activité simultanée d'un neurone présynaptique et d'un neurone postsynaptique renforcerait la synapse qui les connecte. Dans le mécanisme de coïncidence prémodulatrice, proposé en 1963, la synapse entre deux neurones est renforcée même si le neurone postsynaptique n'est pas actif, lorsqu'un troisième neurone, le neurone modulateur, est actif en même temps que le neurone présynaptique.  1, record 8, French, - m%C3%A9canisme%20de%20co%C3%AFncidence%20pr%C3%A9modulatrice

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 CONT

Two cellular mechanisms are hypothesized for associative changes in synaptic strength during learning. The pre-post coincidence mechanism, proposed by Donald O. Hebb in 1949, points that coincident activity in the presynaptic and postsynaptic neurons is critical for strengthening the connections between them. The pre-modulatory coincidence mechanism proposed in 1963, based on studies on the nervous system of the marine snail Aplysia, holds that the connection can be strengthened without activity of the postsynaptic cell when a third neuron, the modulatory neuron, is active at the same time as the presynaptic neuron.  1, record 9, English, - pre%2Dpost%20coincidence%20mechanism

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 CONT

Deux mécanismes cellulaires pourraient expliquer les changements associatifs de la force des synapses au cours de l'apprentissage. Dans le mécanisme de coïncidence pré-post, proposé par Donald Hebb en 1949, l'activité simultanée d'un neurone présynaptique et d'un neurone postsynaptique renforcerait la synapse qui les connecte. Dans le mécanisme de coïncidence prémodulatrice, proposé en 1963, la synapse entre deux neurones est renforcée même si le neurone postsynaptique n'est pas actif, lorsqu'un troisième neurone, le neurone modulateur, est actif en même temps que le neurone présynaptique.  1, record 9, French, - m%C3%A9canisme%20de%20co%C3%AFncidence%20pr%C3%A9%2Dpost

Record 9,  Textual support,  Spanish

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 CONT

... the most critical tissue-disruption mechanism and the only reliable mechanism available to the handgun bullet user.  1, record 10, English, - tissue%2Ddisruption%20mechanism

Record 10,  Textual support,  French

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 CONT

The issues-and-examples paradigm proposes a mechanism for determining when and how knowledge could be presented by a coach to motivate learning in the performance of an activity. If there is evidence of weaknesses, critical issues are mentioned when the student has just failed to use them, that is, in the context of moves she has just been thinking about. That makes the issues relevant. Then they are introduced with the help of concrete examples in the form of better solutions for the current moves. At that time, the student perceives them as crucial to successfully completing the activity. That makes them memorable.  1, record 11, English, - issues%2Dand%2Dexamples%20paradigm

Record 11,  Textual support,  French

Record 11,  Textual support,  Spanish