TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

[Cooking with cannabis] largely involves decarboxylation, a delicate process wherein the cannabis flower is heated for a period of time to activate the [tetrahydrocannabinol].  2, record 1, English, - decarboxylation

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Réaction au cours de laquelle une molécule d'anhydride carbonique est enlevée d'une molécule contenant un groupe carboxyle.  2, record 1, French, - d%C3%A9carboxylation

Record number: 1, Textual support number: 1 CONT

Afin d'obtenir les effets recherchés, le cannabis doit d'abord être séché et ensuite chauffé. En l'absence de chaleur, la fleur de cannabis contient seulement [de l'acide tétrahydrocannabinolique], un agent non psychoactif. C'est le processus de décarboxylation qui permettra à l'utilisateur de jouir des effets psychoactifs du produit.  3, record 1, French, - d%C3%A9carboxylation

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 DEF

Reacción de eliminación del dióxido de carbono existente en distintos compuestos orgánicos, generalmente ácidos carboxílicos.  2, record 1, Spanish, - decarboxilaci%C3%B3n

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

An amino alcohol... found in cephalins and phospholipids, and derived metabolically by decarboxylation of serine.  8, record 2, English, - 2%2Daminoethanol

Record number: 2, Textual support number: 2 DEF

A colorless liquid basic amino alcohol ... made usually from ammonia and ethylene oxide and used chiefly as a solvent, in scrubbing acidic gases from gas streams, in making detergents, and in synthesis (as of pharmaceuticals).  9, record 2, English, - 2%2Daminoethanol

Record number: 2, Textual support number: 1 OBS

2-aminoethanol: form recommended by the IUPAC (International Union of Pure and Applied Chemistry).  10, record 2, English, - 2%2Daminoethanol

Record number: 2, Textual support number: 2 OBS

ethanolamine: a commercial and incorrect form.  10, record 2, English, - 2%2Daminoethanol

Record number: 2, Textual support number: 3 OBS

monoethanolamine: incorrect form.  10, record 2, English, - 2%2Daminoethanol

Record number: 2, Textual support number: 4 OBS

Chemical formula: C₂H₇NO or HOCH₂CH₂NH₂or NH₂(CH₂)₂OH or HO-CH₂-CH₂-NH₂ or NH₂CH₂CH₂OH  11, record 2, English, - 2%2Daminoethanol

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Produit chimique se présentant sous la forme d'un liquide incolore, visqueux, hygroscopique, à faible odeur ammoniacale, que l'on utilise pour la purification des gaz, la fabrication d'agents tensioactifs, d'inhibiteurs de corrosion, d'insecticides, de produits pharmaceutiques et en synthèse organique.  8, record 2, French, - 2%2Damino%C3%A9thanol

Record number: 2, Textual support number: 1 OBS

2-aminoéthanol : forme recommandée par l'UICPA (Union internationale de chimie pure et appliquée).  1, record 2, French, - 2%2Damino%C3%A9thanol

Record number: 2, Textual support number: 2 OBS

monoéthanolamine : forme incorrecte.  1, record 2, French, - 2%2Damino%C3%A9thanol

Record number: 2, Textual support number: 3 OBS

éthanolamine : terme commercial impropre.  1, record 2, French, - 2%2Damino%C3%A9thanol

Record number: 2, Textual support number: 4 OBS

Formule chimique : C₂H₇NO ou HOCH₂CH₂NH₂ou NH₂(CH₂)₂OH ou HO-CH₂-CH₂-NH₂ ou NH₂CH₂CH₂OH  8, record 2, French, - 2%2Damino%C3%A9thanol

Record 2,  Textual support,  Spanish

Record number: 2, Textual support number: 1 OBS

Líquido viscoso; incoloro, de olor amoniacal. Soluble en tetracloruro de carbono, alcohol y cloroformo. Combustible. Muy tóxico e irritante.  3, record 2, Spanish, - colamina

Record number: 2, Textual support number: 2 OBS

Fórmula química: C₂H₇NO o HOCH₂CH₂NH₂o NH₂(CH₂)₂OH o HO-CH₂-CH₂-NH₂ o NH₂CH₂CH₂OH  4, record 2, Spanish, - colamina

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

An enzyme that catalyzes the decarboxylation of malic acid coupled to the reduction of NAD(P).  2, record 3, English, - malic%20enzyme

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

[...] carboxylation de l'acide pyruvique en acide malique, calalysée par l'«enzyme malique» et oxydation de l'acide malique en acide oxalo-acétique [...]  2, record 3, French, - enzyme%20malique

Record 3,  Textual support,  Spanish

Record number: 3, Textual support number: 1 OBS

Tradicionalmente, la Real Academia Española (RAE) admitía únicamente el género femenino para el sustantivo enzima; así fue hasta 1984, fecha en que pasó a considerarlo de género ambiguo, que puede funcionar por igual como masculino y como femenino. El uso, no obstante, parece haberse decantado claramente en español por el femenino, que hoy se emplea en el 90% de los casos [...]  3, record 3, Spanish, - enzima%20m%C3%A1lica

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

The product of decarboxylation of tyrosine. It is closely related to epinephrine, although not a precursor.  2, record 4, English, - tyramine

Record 4,  Textual support,  French

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

A colorless liquid resulting from the decarboxylation of anisic acid or the methylation of phenol [that is used as a] flavoring [agent] for various sweet-tasting foods.  5, record 5, English, - anisole

Record number: 5, Textual support number: 1 OBS

Chemical formulas: C₆H₅OCH₃ or CH₃O-C₆H₅  6, record 5, English, - anisole

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Produit chimique se présentant sous la forme d'un liquide incolore, d'odeur agréable, soluble dans l'alcool, l'éther, insoluble dans l'eau, obtenu par décarboxylation de l'acide anisique ou par méthylation du phénol, utilisé comme aromatisant pour diverses préparations sucrées, dans les parfums synthétiques, les insecticides, et en microscopie.  5, record 5, French, - anisole

Record number: 5, Textual support number: 1 OBS

Formules chimiques : C₆H₅OCH₃ ou CH₃O-C₆H₅  5, record 5, French, - anisole

Record 5,  Textual support,  Spanish

Record number: 5, Textual support number: 1 DEF

Líquido incoloro de olor agradable. Soluble en alcohol y éter. Insoluble en agua. Muy tóxico por via inhalatoria. Inflamable.  2, record 5, Spanish, - anisol

Record number: 5, Textual support number: 1 OBS

Fórmulas químicas : C₆H₅OCH₃ o CH₃O-C₆H₅  3, record 5, Spanish, - anisol

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 CONT

Examples are the reduction of pyruvate to lactate, the reductive decarboxylation of pyruate to ethanol, and the reduction of acetoacetate to buryrate.  2, record 6, English, - acetoacetate

Record number: 6, Textual support number: 1 OBS

A product used in biotechnology, for the production of feedstock chemicals.  3, record 6, English, - acetoacetate

Record number: 6, Textual support number: 2 OBS

Chemical formulas: CH₃-CO-CH₂-CO₂ or CH₃-CO-CH₂-COO-  4, record 6, English, - acetoacetate

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 DEF

Nom générique des sels et esters de l'acide acétylacétique [...] ainsi que des produits de substitution métalliques.  3, record 6, French, - ac%C3%A9toac%C3%A9tate

Record number: 6, Textual support number: 1 OBS

Formules chimiques : CH₃-CO-CH₂-CO₂ ou CH₃-CO-CH₂-COO-  4, record 6, French, - ac%C3%A9toac%C3%A9tate

Record 6,  Textual support,  Spanish

Record number: 6, Textual support number: 1 CONT

Los cuerpos cetónicos (acetoacetato, acetona y beta hidroxibutirato) se forman en [el] hígado [...]  1, record 6, Spanish, - acetoacetato

Record number: 6, Textual support number: 1 OBS

Fórmulas químicas : CH₃-CO-CH₂-CO₂ o CH₃-CO-CH₂-COO-  2, record 6, Spanish, - acetoacetato

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 DEF

An inhibitor... of the decarboxylation of peripheral levodopa to dopamine, which does not penetrate the central nervous system,... is used orally, in combination with levodopa, as an antiparkinsonian agent, and has been used in the treatment of Lesch-Nyhan syndrome and Gilles de la Tourette syndrome.  4, record 7, English, - %282S%29%2D2%2Dhydrazino%2D2%2Dmethyl%2D3%2D%283%2C4%2Ddihydroxyphenyl%29propanoic%20acid

Record number: 7, Textual support number: 1 OBS

(2S)-2-hydrazino-2-methyl-3- (3,4-dihydroxyphenyl)propanoic acid: The capital letter "S" must be italicized; form recommended by the IUPAC (International Union of Pure and Applied Chemistry).  1, record 7, English, - %282S%29%2D2%2Dhydrazino%2D2%2Dmethyl%2D3%2D%283%2C4%2Ddihydroxyphenyl%29propanoic%20acid

Record number: 7, Textual support number: 2 OBS

Chemical formula: C₁₀H₁₄N₂O₄·H₂O  5, record 7, English, - %282S%29%2D2%2Dhydrazino%2D2%2Dmethyl%2D3%2D%283%2C4%2Ddihydroxyphenyl%29propanoic%20acid

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

Antiparkinsonien [par] administration simultanée de carbidopa et de lévodopa [...]  3, record 7, French, - acide%20%282S%29%2D2%2Dhydrazino%2D2%2Dm%C3%A9thyl%2D3%2D%283%2C4%2Ddihydroxyph%C3%A9nyl%29propano%C3%AFque

Record number: 7, Textual support number: 1 OBS

acide (2S)-2-hydrazino-2-méthyl-3-(3,4-dihydroxyphényl)propanoïque : La lettre majuscule «S» s'écrit en italique; forme recommandée par l'UICPA (Union internationale de chimie pure et appliquée).  1, record 7, French, - acide%20%282S%29%2D2%2Dhydrazino%2D2%2Dm%C3%A9thyl%2D3%2D%283%2C4%2Ddihydroxyph%C3%A9nyl%29propano%C3%AFque

Record number: 7, Textual support number: 2 OBS

Formule chimique : C₁₀H₁₄N₂O₄·H₂O  4, record 7, French, - acide%20%282S%29%2D2%2Dhydrazino%2D2%2Dm%C3%A9thyl%2D3%2D%283%2C4%2Ddihydroxyph%C3%A9nyl%29propano%C3%AFque

Record 7,  Textual support,  Spanish

Record number: 7, Textual support number: 1 OBS

Fórmula química: C₁₀H₁₄N₂O₄·H₂O  2, record 7, Spanish, - carbidopa

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

Pyridoxal-phosphate(PLP, pyridoxal-5’-phosphate) is a coenzyme of many enzymatic reactions. It is the active form of vitamin B6 which comprises three natural organic compounds, pyridoxal, pyridoxamine and pyridoxine. PLP acts as a coenzyme in all transamination reactions, and in some decarboxylation and deamination reactions of amino acids.  8, record 8, English, - pyridoxal%20phosphate

Record number: 8, Textual support number: 1 OBS

Chemical formula: C₈H₁₀NO₆P  9, record 8, English, - pyridoxal%20phosphate

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 DEF

Coenzyme des transaminases qui joue le rôle d'accepteur d'ammoniac dans la transformation des alpha-aminoacides en alpha-cétoacides.  7, record 8, French, - phosphate%20de%20pyridoxal

Record number: 8, Textual support number: 1 CONT

Le terme vitamine B6 désigne 6 composés : le pyridoxal (PL), la pyridoxine (PN), la pyridoxamine (PM) et leurs dérivés phosphorylés, le pyridoxal 5'-phosphate (PLP), la pyridoxamine 5'-phosphate (PMP), la pyridoxine 5'-phosphate (PNP).  8, record 8, French, - phosphate%20de%20pyridoxal

Record number: 8, Textual support number: 1 OBS

Formule chimique : C₈H₁₀NO₆P  9, record 8, French, - phosphate%20de%20pyridoxal

Record 8,  Textual support,  Spanish

Record number: 8, Textual support number: 1 CONT

La coenzima que contiene un aldehído, el fosfato de piridoxal (PLP) que es un derivado de la piridoxina (vitamina B6).  1, record 8, Spanish, - fosfato%20de%20piridoxal

Record number: 8, Textual support number: 2 CONT

La Vitamina B6 es una vitamina hidrosoluble que se presenta en seis formas diferentes: piridoxal (PL), piridoxina (PN), piridoxamina (PM) y sus correspondientes ésteres fosfóricos, 5'fosfato de piridoxal (PLP), 5'fosfato de piridoxina (PNP) y 5'fosfato de piridoxamina (PMP).  3, record 8, Spanish, - fosfato%20de%20piridoxal

Record number: 8, Textual support number: 1 OBS

Fórmula química: C₈H₁₀NO₆P  5, record 8, Spanish, - fosfato%20de%20piridoxal

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 DEF

The substance formed by decarboxylation of histidine [which] is released from mast cells during the allergic response.  2, record 9, English, - histamine

Record number: 9, Textual support number: 1 CONT

When a person is exposed to an allergen ... the bloodstream sends a crowd of circulating white blood cells to the site of contact. ... Some of those white cells, the basophils, release histamines, chemicals that increase local blood flow; cause leaks in small blood vessels; and spark a flood of more white cells.  3, record 9, English, - histamine

Record number: 9, Textual support number: 1 OBS

It stimulates the contraction of smooth muscle and increase vascular permeability.  2, record 9, English, - histamine

Record 9,  Textual support,  French

Record number: 9, Textual support number: 1 DEF

Produit chimique libéré dans le corps humain par l'interaction d'un allergène avec un anticorps fixé sur un mastocyte ou un basophile.  2, record 9, French, - histamine

Record number: 9, Textual support number: 1 CONT

L'histamine est le premier médiateur connu et peut entraîner toute une série de phénomènes inflammatoires caractéristiques de la réaction allergique immédiate.  2, record 9, French, - histamine

Record number: 9, Textual support number: 2 CONT

L'histamine est contenue à l'intérieur des mastocytes et des basophiles [...] L'histaminolibération survient principalement au cours des réactions d'hypersensibilité immédiate, lorsqu'un antigène, réintroduit dans l'organisme, réagit avec un anticorps fixé sur la membrane du mastocyte. [L]'histamine provoque une dilatation des capillaires avec augmentation de la perméabilité locale [...]  3, record 9, French, - histamine

Record 9,  Textual support,  Spanish

Record number: 9, Textual support number: 1 DEF

Sustancia orgánica presente en los tejidos vegetales y animales, que estimula secreciones e interviene en la actividad de los vasos sanguíneos. Está presente en las reacciones alérgicas.  2, record 9, Spanish, - histamina

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 DEF

Neoplasm of APUD cells.  1, record 10, English, - apudoma

Record number: 10, Textual support number: 1 OBS

APUD=amine content and/or precursor uptake and decarboxylation)(e. g. carcinoid tumour, insulinoma).  1, record 10, English, - apudoma

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 DEF

Pathologie tumorale intéressant un type cellulaire du système APUD.  1, record 10, French, - apudome

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 DEF

Addition of a carboxyl group into a molecule.  2, record 11, English, - carboxylation

Record number: 11, Textual support number: 1 CONT

Carbon dioxide assimilation. In C3(Calvin cycle) plants, carbon reduction starts with the carboxylation of ribulose biphosphate(Rubisco) and with a first product(phosphoglyceric acid) being reduced to a 3-carbon sugar. In C4 plants, CO₂ is assimilated into the 4-carbon oxaloacetic acid by the enzyme PEP carboxylase, decarboxylation takes place and the liberated CO₂ is refixed through the normal Calvin cycle in bundle sheath chloroplasts. Succulents have a malate-based CAM cycle.  3, record 11, English, - carboxylation

Record 11,  Textual support,  French

Record number: 11, Textual support number: 1 DEF

Fixation dans une molécule du radical carboxyle par substitution à un atome d'hydrogène ou à un atome de métal.  2, record 11, French, - carboxylation

Record number: 11, Textual support number: 1 OBS

La carboxylation est une réaction synthétique utile, qui se fait toujours par l'attaque d'un composé nucléophile sur l'anhydride carbonique; dans certains cas, il s'agit d'une réaction industrielle importante, comme la carboxylation de l'ammoniac, qui donne l'acide carbamique, ou celle du phénate de sodium, qui donne le salicylate de sodium.  2, record 11, French, - carboxylation

Record 11,  Textual support,  Spanish

Record number: 11, Textual support number: 1 DEF

Reacción química en la que un carbanión interacciona con CO₂, formándose un anión carboxilato.  1, record 11, Spanish, - carboxilaci%C3%B3n

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 DEF

A poisonous, sirupy foul smelling substance arising by decarboxylation of lysine in bacteria and in decomposing flesh.  2, record 12, English, - cadaverine

Record number: 12, Textual support number: 1 OBS

It is a skin irritant and possible sensitizing agent.  2, record 12, English, - cadaverine

Record 12,  Textual support,  French

Record number: 12, Textual support number: 1 CONT

Au cours de son activité, une bactérie, qui est une cellule, produit des déchets (cadavérine et putrescine) qu'elle rejette. Ces déchets ont un fort pouvoir toxique pour les bactéries.  2, record 12, French, - cadav%C3%A9rine

Record 12,  Textual support,  Spanish

Record number: 12, Textual support number: 1 DEF

Uno de los productos resultantes de la descomposición de los cuerpos animales. Líquido fumante incoloro, soluble en agua y alcohol, ligeramente soluble en éter. Muy tóxico e irritante.  1, record 12, Spanish, - cadaverina

Record number: 12, Textual support number: 1 OBS

Fórmula química: NH₂ (CH₂)₅ NH₂.  2, record 12, Spanish, - cadaverina

Record 13,  Textual support,  English

Record number: 13, Textual support number: 1 DEF

Coenzyme consisting of pantothenic acid linked to a mononucleotide based on adenine. It is an intermediate involved in the transfer of acetyl groups (with which it combines to form acetyl-CoA) and other fatty acyl groups which are bound to a thiol group on the molecule. It plays an important role in fatty acid synthesis and oxidation, as well as in the first step of the TCA cycle.  5, record 13, English, - coenzyme%20A

Record number: 13, Textual support number: 1 CONT

CoA... was discovered as an essential cofactor for the acetylation of sulfanilamide in the liver and of choline in the brain. It has been established that CoA is involved in many biochemical reactions in the body as an "activator" of normally less reactive carbon fragments and a "transferer" of these fragments to different molecules.... After oxidative decarboxylation of pyruvic acid, CoA combines with the two-carbon acetate fragment to form acetyl-CoA or "active" acetate. Coenzyme A is necessary for the activation, synthesis, and degradation of fatty acids. Synthesis of cholesterol and ultimately the production of steroid hormones are also coenzyme A dependent.  6, record 13, English, - coenzyme%20A

Record number: 13, Textual support number: 1 OBS

CoA and CoA-SH are abbreviations for coenzyme A.  3, record 13, English, - coenzyme%20A

Record 13,  Textual support,  French

Record number: 13, Textual support number: 1 DEF

Coenzyme des transacétylases, qui, grâce à son groupement fonctionnel thiol (présent dans la molécule de mercapto-éthylamine qui le compose), se combine à différents métabolites par une liaison «riche en énergie».  3, record 13, French, - coenzyme%20A

Record number: 13, Textual support number: 1 CONT

Le co-enzyme A dérive d'une vitamine du groupe B, l'acide pantothénique, qui est combiné, d'une part à un phosphate lequel est lié par une liaison pyrophosphate à une molécule d'adénosine 3'-5' diphosphate, d'autre part à une molécule de thio-éthylamine (ou cysté-amine). C'est le groupement thiol de cette dernière qui est la partie active de la molécule : son H peut être substitué par divers radicaux acyle (notamment acétyle) pour former des acyl-co-enzymes A ou acides gras activés qui chimiquement sont des thio-esters, composés très réactifs (acétyl-co-enzyme A, par exemple).  4, record 13, French, - coenzyme%20A

Record number: 13, Textual support number: 1 OBS

CoA et CoA-SH sont des abréviations de coenzyme A.  2, record 13, French, - coenzyme%20A

Record number: 13, Textual support number: 2 OBS

Termes vieillis à éviter : - co-acétylase - co-acylase - co-enzyme d'activation - coenzyme des acylations - coenzyme acétylant - coenzyme de Lipmann.  2, record 13, French, - coenzyme%20A

Record 13,  Textual support,  Spanish

Record 14,  Textual support,  English

Record number: 14, Textual support number: 1 CONT

Maple syrup urine disease(MSUD). This disorder, also called branched-chain a-ketoaciduria, derives its name from the burnt-sugar smell of affected infants. MSUD is caused by impaired branched chain a-ketoacid dehydrogenase, which catalyzes decarboxylation of the a-ketoacid derivatives of all three of these amino acids.  1, record 14, English, - maple%20syrup%20urine%20disease

Record 14,  Textual support,  French

Record number: 14, Textual support number: 1 DEF

Maladie héréditaire à transmission autosomique récessive, liée à un déficit de l'enzyme catalysant la décarboxylation oxydative des cétoacides dérivant des acides ramifiés (leucine, isoleucine et valine).  3, record 14, French, - maladie%20des%20urines%20%C3%A0%20odeur%20de%20sirop%20d%27%C3%A9rable

Record 14,  Textual support,  Spanish

Record 15,  Textual support,  English

Record number: 15, Textual support number: 1 DEF

A monoamine neurotransmitter formed in the brain by the decarboxylation of dopa and essential to the normal functioning of the central nervous system.  2, record 15, English, - dopamine

Record number: 15, Textual support number: 1 CONT

Dopamine. ... is one of the most commonly used drugs to treat many forms of shock, probably related to its unique dose-dependent pharmacologic effects. Dopamine is the naturally occurring precursor of norepinephrine.  3, record 15, English, - dopamine

Record 15,  Textual support,  French

Record number: 15, Textual support number: 1 DEF

Métabolite de la dopa et précurseur de la noradrénaline et de l'adrénaline.  1, record 15, French, - dopamine

Record 15,  Textual support,  Spanish

Record 16,  Textual support,  English

Record number: 16, Textual support number: 1 CONT

Lysine has two distinct biosynthetic pathways, the diaminopimelic acid pathway and the [alpha]-aminoadipic acid pathway. The diaminopimelic acid pathway operates in bacteria, some lower fungi, algae, and higher plants. It begins with condensation of pyruvate with aspartate ß-semialdehyde and ends with decarboxylation of diaminopimelate. Diaminopimelate is an important constituent of bacterial cell walls. The [alpha]-aminoadipic acid pathway is less widespread and functions in other lower fungi, in higher fungi, and in the protist Euglena.  2, record 16, English, - diaminopimelate

Record 16,  Textual support,  French

Record number: 16, Textual support number: 1 DEF

Sel de l'acide diaminopimélique.  2, record 16, French, - diaminopim%C3%A9late

Record number: 16, Textual support number: 1 CONT

Méthode précise de dosage du diaminopimélate, étude de sa présence chez les animaux axéniques et embryons de poulet.  3, record 16, French, - diaminopim%C3%A9late

Record 16,  Textual support,  Spanish

Record 17,  Textual support,  English

Record number: 17, Textual support number: 1 DEF

A compound that serves as a component of cell wall mucopeptide in some bacteria and as a source of lysine in all bacteria.  3, record 17, English, - diaminopimelic%20acid

Record number: 17, Textual support number: 1 CONT

Design and synthesis of inhibitors of biosynthesis of peptidoglycan, a key constituent of bacterial cell walls and a target for broad spectrum antibiotics. Special emphasis is on blocking formation and utilization of diaminopimelic acid (DAP) as well as preventing polymerization of the polysaccharide backbone.  2, record 17, English, - diaminopimelic%20acid

Record number: 17, Textual support number: 2 CONT

Lysine has two distinct biosynthetic pathways, the diaminopimelic acid pathway and the [alpha]-aminoadipic acid pathway. The diaminopimelic acid pathway operates in bacteria, some lower fungi, algae, and higher plants. It begins with condensation of pyruvate with aspartate ß-semialdehyde and ends with decarboxylation of diaminopimelate. Diaminopimelate is an important constituent of bacterial cell walls. The [alpha]-aminoadipic acid pathway is less widespread and functions in other lower fungi, in higher fungi, and in the protist Euglena.  4, record 17, English, - diaminopimelic%20acid

Record number: 17, Textual support number: 1 OBS

DAP: This might be an in-house or a non-recognized abbreviation; not to be used alone, to avoid any risk of confusion.  5, record 17, English, - diaminopimelic%20acid

Record 17,  Textual support,  French

Record number: 17, Textual support number: 1 CONT

diaminopimélate : Sel de l'acide diaminopimélique.  4, record 17, French, - acide%20diaminopim%C3%A9lique

Record number: 17, Textual support number: 2 CONT

On utilise pour obtenir un «confinement biologique», des souches d'E. coli réceptrices d'ADN étranger qui sont exigeantes en acide diaminopimélique (DAP), substance uniquement d'origine bactérienne et peu répandue dans l'environnement. On a pu montrer à l'aide de modèles gnotoxéniques que les parois de certaines bactéries de la flore du tube digestif pouvaient servir de source de DAP aux mutants exigeants et permettre leur croissance «in vivo».  2, record 17, French, - acide%20diaminopim%C3%A9lique

Record number: 17, Textual support number: 1 OBS

DAP : abréviation non officielle; ne pas l'utiliser seule, pour éviter tout risque de confusion.  5, record 17, French, - acide%20diaminopim%C3%A9lique

Record 17,  Textual support,  Spanish

Record 18,  Textual support,  English

Record number: 18, Textual support number: 1 CONT

The name APUD was coined for amine precursor uptake and decarboxylation; this process is similar to that seen in neurones. APUD cells were named by Pearse to organize his observations on peptide-secreting cells, particularly those from the GI tract. These cells take up precursors of biologically active amines to produce active amine through intracellular decarboxylation with subsequent storage of the amine product in secretory vesicles. APUD cells may have neuroectodermal and endodermal origins but this remains to be proven.  1, record 18, English, - amine%20precursor%20uptake%20and%20decarboxylation

Record 18,  Textual support,  French

Record number: 18, Textual support number: 1 CONT

Un certain nombre de cellules du SED sont des cellules du système APUD de Pearse, cellules capables de capter les précurseurs des amines biogènes et de les décarboxyler (Amine Precursor Uptake and Decarboxylation). Elles sécrètent des hormones polypeptidiques et/ou des amines biogènes dont certaines sont des neurotransmetteurs. L'origine embryonnaire de ces cellules est neurectoblastique, à partir des crêtes neurales, tout comme les neurones; on parle de cellules neuro-endocrines.  1, record 18, French, - amine%20precursor%20uptake%20and%20decarboxylation

Record number: 18, Textual support number: 1 OBS

SED : système endocrinien diffus.  2, record 18, French, - amine%20precursor%20uptake%20and%20decarboxylation

Record 18,  Textual support,  Spanish

Record 19,  Textual support,  English

Record number: 19, Textual support number: 1 DEF

C8 H14 02 S2. A compound which participates in the enzymatic oxidative decarboxylation of X-Keto acids in a stage between thiamine pyrophosphate and coenzyme A.  1, record 19, English, - lipoic%20acid

Record 19,  Textual support,  French

Record 19,  Textual support,  Spanish