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DENDROASPIS POLYLEPIS [2 records]

Record 1 2016-05-13

English

Subject field(s)
  • Reptiles and Amphibians
Universal entry(ies)
CONT

The mambas(Dendroaspis) are much feared and ill-famed in Africa than are the resident cobras. The most familiar is perhaps the black mamba(Dendroaspis polylepis), the largest venomous snake in Africa.

French

Domaine(s)
  • Reptiles et amphibiens
Entrée(s) universelle(s)

Spanish

Save record 1

Record 2 2007-12-21

English

Subject field(s)
  • Toxicology
  • Cardiovascular System
DEF

[A] 60-amino acid [polypeptide], isolated from venom of the black mamba(Dendroaspis polylepis polylepis), that [blocks] voltage-dependent L-type Ca2+ channels.

French

Domaine(s)
  • Toxicologie
  • Système cardio-vasculaire
CONT

La calciseptine, isolée à partir du venin de Dendroaspis polylepis, interagit sélectivement avec le canal calcium de type L situé principalement au niveau des cellules cardiaques ventriculaires ou des cellules musculaires lisses aortiques. Sa fixation provoque le blocage de ce canal ionique et l'abolition du couplage excitation-contraction des cellules musculaires lisses et finalement à l'inhibition de la contraction cardiaque.

Spanish

Save record 2

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