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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 DEF

Bacterial enzyme that catalyzes the chemical alteration of certain bases of DNA by methylation of nucleotides within restriction recognition sites corresponding to its own restriction enzymes. This protects its own DNA against attack.  2, record 1, English, - modification%20enzyme

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Enzyme d'origine bactérienne dont le rôle est de protéger le DNA originel bactérien contre l'action de ses propres enzymes de restriction en méthylant une base sur chaque brin au niveau des points de coupure.  2, record 1, French, - enzyme%20de%20modification

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

A proto-oncogene that has been activated within the host so that oncogenicity results.  1, record 2, English, - cellular%20oncogene

Record number: 2, Textual support number: 1 OBS

proto-oncogene : a normal cellular gene that with alteration, such as by mutation, DNA rearrangement, or nearby insertion of viral DNA, becomes an active oncogene; most proto-oncogenes are believed to normally function in cell growth and differentiation.  1, record 2, English, - cellular%20oncogene

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

Les oncogènes cellulaires (c-onc) correspondent à la version mutée de gènes intervenant dans de nombreuses fonctions normales de la cellule, et les oncogènes viraux (v-onc) sont constitués par des gènes cellulaires qui ont été jadis empruntés par les rétrovirus.  1, record 2, French, - oncog%C3%A8ne%20cellulaire

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

Alteration in DNA involving a change in a single base pair at a particular site.  1, record 3, English, - nucleotide%20substitution

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Remplacement d'une base par une autre dans la molécule d'ADN pouvant conduire à une mutation dans le génome.  2, record 3, French, - substitution%20de%20bases

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

There are some questions as to methodology [concerning research in molecular and developmental genetics] Things such as possible difficulties with interpretation of data from using heterologous biochemical assays and correlating in vitro protein phosphorylation sites with in vivo sites of phosphorylation could have been better addressed ....  1, record 4, English, - protein%20phosphorylation

Record number: 4, Textual support number: 2 CONT

Protein kinase C-mediated bidirectional regulation of DNA synthesis, RB protein phosphorylation, and cyclin-dependent kinases in human vascular endothelial cells... Agents which activate protein kinase C or otherwise enhance protein phosphorylation caused a substantial decrease in A beta production in vitro... The muscarinic inhibition of cyclic AMP(cAMP) mediated contractile effects may not only be the result of a reduction in cAMP levels, but may also involve cAMP linked protein phosphorylation in the heart... Recent studies in Alzheimer brains have shown aberrant protein phosphorylation, suggesting an alteration in protein kinases and/or phosphoprotein phosphatases... [Source : PASCAL database].  2, record 4, English, - protein%20phosphorylation

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 CONT

L'exemple le plus ancien et le plus célèbre des régulations par phosphorylation de protéines est celui de la glycogène phosphorylase, déjà rencontrée comme protéine allostérique. Nous savons qu'un 2e mécanisme règle l'activité de la protéine puisqu'elle peut passer par phosphorylation d'une forme b peu active à une forme a très active. Une seule phosphorylation sur chaque sous-unité du dimère suffit [...]  1, record 4, French, - phosphorylation%20de%20prot%C3%A9ines

Record 4,  Textual support,  Spanish