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The Government of Canada’s terminology and linguistic data bank.
DNA LIGASE [4 records]
Record 1 - internal organization data 2013-07-18
Record 1, English
Record 1, Subject field(s)
- Bioengineering
- Biotechnology
- Biochemistry
Record 1, Main entry term, English
- ligase chain reaction
1, record 1, English, ligase%20chain%20reaction
correct
Record 1, Abbreviations, English
- LCR 1, record 1, English, LCR
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The ligase chain reaction(LCR) will use DNA ligase, the enzyme which joins two DNA molecules together, to link two oligonucleotides together if a target DNA is present. 1, record 1, English, - ligase%20chain%20reaction
Record 1, French
Record 1, Domaine(s)
- Technique biologique
- Biotechnologie
- Biochimie
Record 1, Main entry term, French
- ligation répétitive d'oligonucléotides
1, record 1, French, ligation%20r%C3%A9p%C3%A9titive%20d%27oligonucl%C3%A9otides
correct, feminine noun
Record 1, Abbreviations, French
- LCR 1, record 1, French, LCR
correct, feminine noun
Record 1, Synonyms, French
- réaction de ligature en chaîne 2, record 1, French, r%C3%A9action%20de%20ligature%20en%20cha%C3%AEne
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Technique qui consiste à synthétiser deux oligonucléotides d'une vingtaine de paires de bases en s'hybridant au niveau de la séquence mutée avec l'ADN. 1, record 1, French, - ligation%20r%C3%A9p%C3%A9titive%20d%27oligonucl%C3%A9otides
Record number: 1, Textual support number: 1 CONT
Si la séquence à analyser est normale, les deux oligonucléotides sont exactement bout à bout, ce qui permet à la ligase ajoutée d'agir et donc de les ligaturer. Si la séquence est mutée, la première base du second oligonucléotide ne peut pas s'hybrider, les deux oligonucléotides ne sont pas bout à bout : la ligase ne peut pas agir et les deux nucléotides ne sont pas ligaturés. 1, record 1, French, - ligation%20r%C3%A9p%C3%A9titive%20d%27oligonucl%C3%A9otides
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioingeniería
- Biotecnología
- Bioquímica
Record 1, Main entry term, Spanish
- reacción en cadena de la ligasa
1, record 1, Spanish, reacci%C3%B3n%20en%20cadena%20de%20la%20ligasa
correct, feminine noun
Record 1, Abbreviations, Spanish
- LCR 1, record 1, Spanish, LCR
correct, feminine noun
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Técnica para detectar y amplificar secuencias diana de ADN. 1, record 1, Spanish, - reacci%C3%B3n%20en%20cadena%20de%20la%20ligasa
Record number: 1, Textual support number: 1 OBS
Primero se sintetizan dos oligonucleótidos, que sean complementarios a la secuencia diana completa, uno por el extremo 5' y el otro por el 3'. Si la secuencia diana se encuentra en la muestra de ADN que se está examinando, los oligonucleótidos se fijan a ella reuniendo sus extremos en el centro y, mediante una ligasa termoestable, se unen para formar un polinucleótido completo. El ligamiento no se producirá si la muestra no contiene la secuencia diana o si el empalme entre la secuencia diana y los oligonucleótidos es imperfecto. Sometido a una temperatura elevada, el nuevo polinucleótido se disocia del molde de ADN original; después de bajar la temperatura, éste y el ADN original servirán de moldes para un segundo ciclo de hibridación, ligamiento y disociación térmica. En cada ciclo se duplica el número de nuevos polinucleótidos completos. 1, record 1, Spanish, - reacci%C3%B3n%20en%20cadena%20de%20la%20ligasa
Record 2 - internal organization data 2012-12-20
Record 2, English
Record 2, Subject field(s)
- Genetics
- Molecular Biology
Record 2, Main entry term, English
- Okazaki fragments
1, record 2, English, Okazaki%20fragments
correct, plural
Record 2, Abbreviations, English
Record 2, Synonyms, English
- Okazaki pieces 2, record 2, English, Okazaki%20pieces
correct, plural, less frequent
- Okazaki segments 2, record 2, English, Okazaki%20segments
correct, plural, less frequent
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
The short lengths of DNA produced on the lagging strand during DNA replication. 3, record 2, English, - Okazaki%20fragments
Record number: 2, Textual support number: 1 OBS
They are rapidly joined by DNA ligase to form a continuous DNA strand. 3, record 2, English, - Okazaki%20fragments
Record 2, Key term(s)
- Okasaki fragments
- Okasaki pieces
- Okasaki segments
Record 2, French
Record 2, Domaine(s)
- Génétique
- Biologie moléculaire
Record 2, Main entry term, French
- fragments d'Okazaki
1, record 2, French, fragments%20d%27Okazaki
correct, masculine noun, plural
Record 2, Abbreviations, French
Record 2, Synonyms, French
- fragments d'Okasaki 2, record 2, French, fragments%20d%27Okasaki
correct, masculine noun, plural, less frequent
- brins d'Okazaki 3, record 2, French, brins%20d%27Okazaki
correct, masculine noun, plural, less frequent
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Fragments de 1 000 à 2 000 nucléotides qui résultent de la synthèse discontinue du brin retardé lors de la réplication de l'ADN. 4, record 2, French, - fragments%20d%27Okazaki
Record 2, Key term(s)
- brins d'Okasaki
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Genética
- Biología molecular
Record 2, Main entry term, Spanish
- fragmentos de Okazaki
1, record 2, Spanish, fragmentos%20de%20Okazaki
correct, masculine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 DEF
Fragmentos de ADN recién sintetizados que se producen durante la replicación discontinua de ADN. 1, record 2, Spanish, - fragmentos%20de%20Okazaki
Record 3 - internal organization data 2012-03-16
Record 3, English
Record 3, Subject field(s)
- Genetics
Record 3, Main entry term, English
- ligation
1, record 3, English, ligation
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
The joining together of nucleic acids using [DNA or RNA] ligase. 2, record 3, English, - ligation
Record 3, French
Record 3, Domaine(s)
- Génétique
Record 3, Main entry term, French
- ligature
1, record 3, French, ligature
correct, feminine noun, standardized
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Formation d'une liaison phosphodiester entre deux polynucléotides. [Définition normalisée par l'AFNOR et reproduite avec son autorisation.] 2, record 3, French, - ligature
Record number: 3, Textual support number: 1 OBS
ligature : terme normalisé par l'AFNOR. 3, record 3, French, - ligature
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2010-04-20
Record 4, English
Record 4, Subject field(s)
- Biochemistry
Record 4, Main entry term, English
- ligase detection reaction
1, record 4, English, ligase%20detection%20reaction
correct
Record 4, Abbreviations, English
- LDR 1, record 4, English, LDR
correct
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
PCR methods can be expensive, time-consuming and tedious. The ligase detection reaction(LDR) can be used as an alternative to PCR. In this method, homologous DNA sequences, which may differ by a single nucleotide, can be distinguished. These DNA sequences provide the templates to which oligonucleotides probes anneal. 1, record 4, English, - ligase%20detection%20reaction
Record 4, French
Record 4, Domaine(s)
- Biochimie
Record 4, Main entry term, French
- réaction de détection de la ligase
1, record 4, French, r%C3%A9action%20de%20d%C3%A9tection%20de%20la%20ligase
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record 4, Spanish
Record 4, Textual support, Spanish
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