TERMIUM Plus^®

Record 1,  Textual support,  English

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The association of several protein monomers into a larger unit; the monomers are held together by the same forces that create secondary and tertiary structure, hydrophobic bonding being the most important.  1, record 1, English, - quaternary%20structure

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The quaternary structure describes the way in which certain, complex, usually intracellular enzymes consist of a number of polypeptide chains associated by means of secondary forces to form multi-subunit enzymes.... Evaluation of the functional significance of the quaternary structure is an important part of fundamental studies on the catalytic properties of enzymes. In some enzymes, which exhibit allosteric properties, the main correlations between subunit interactions and enzyme activity are generally understood. However in many other enzymes considerably less is known about the occurrence of subunit interactions or the significance of the oligomeric structure.  2, record 1, English, - quaternary%20structure

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For example, hemoglobin, A, [alpha subscript 2 beta subscript 2], is composed of two alpha monomers and two beta monomers.  1, record 1, English, - quaternary%20structure

Record 1,  Textual support,  French

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Façon caractéristique dont les chaînes polypeptidiques s'assemblent les unes aux autres dans la conformation native des protéines oligomériques.  2, record 1, French, - structure%20quaternaire

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Contrairement aux structures primaire, secondaire ou tertiaire qui contiennent une seule chaîne polypeptidique, la structure quaternaire implique deux ou plusieurs chaînes. Ces chaînes sont ou ne sont pas identiques, mais dans les deux cas elles sont reliées par des liaisons faibles (non convalentes). [...] Le maintien d'une protéine dans une structure tertiaire et quaternaire déterminée est essentiel pour son activité biologique (enzymatique par exemple).  3, record 1, French, - structure%20quaternaire

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Cet ensemble n'est pas une organisation immuable : c'est un état d'équilibre entre l'association et la dissociation partielle des chaînes.  2, record 1, French, - structure%20quaternaire

Record 1,  Textual support,  Spanish

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Nivel de estructura proteínica en el que varias moléculas individuales se unen y forman una agrupación funcional.  1, record 1, Spanish, - estructura%20cuaternaria

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El ejemplo clásico lo constituye la hemoglobina, un complejo de cuatro unidades.  1, record 1, Spanish, - estructura%20cuaternaria

Record 3,  Textual support,  English

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Contact lens-induced corneal endothelial polymegathism :functional significance and possible mechanisms.  2, record 3, English, - polymegethism

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A theory of corneal endothelial polymegethism and aging.  1, record 3, English, - polymegethism

Record 3,  Textual support,  French

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Il est bien connu que le port de lentille de contact provoque des changements morphologiques (transitoires ou permanents) de l'endothélium cornéen. Un de ces changements permanents est le polymégatisme (variation de la taille des cellules de l'endothélium).  2, record 3, French, - polym%C3%A9gatisme

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

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You are likely to find it difficult to interpret the clinical importance of an effect size(if the weighted average effect is one-half of a standard deviation, is this effect clinically trivial, or is it large?). Once again, you should look for a presentation of the results that conveys their pratical importance(for example by translating the summary effect size back into natural units [3715]). For instance, if clinicians have become familiar with the significance of differences in walk test scores in patients with chronic lung disease, the effect size of a treatment on a number of mesures of functional status(such as the walk test and stair climbing) can be converted back into differences in walk test scores.  1, record 4, English, - summary%20effect%20size

Record 4,  Textual support,  French

Record 4,  Textual support,  Spanish

Record 5,  Textual support,  English

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For occasions when a student wants to understand the structure of a control component in details, STEAMER has a facility called the feedback minilab(Forbus, 1984a), where simulated devices can be assembled and tested. On the minilab's screen, the student has a menu of icons representing abstract functions typical of control devices, such as measuring subcomponents or comparators. She can select these abstract components and assemble them on the screen to construct her own control devices. The minilab is then able to generate code from subcomponent specifications to produce a simulation program for the device. Hence, once a controller has been constructed graphically in this way, it can be integrated into a simulation so that its effects on the embedding system can be observed. As implemented, the minilab has limited tutorial capabilities : it can critique the student's device by locating common bugs and recognizing some instances of known devices. Its pedagogical significance lies in its definition of abstract components in terms that allows simulated devices to be built. It is very important for students to acquire this vocabulary of functional abstractions, and the minilab helps root the abstractions’ meaning in direct experiments.  1, record 5, English, - feedback%20minilab

Record 5,  Textual support,  French

Record 5,  Textual support,  Spanish