TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

... fundus autofluorescence(FAF) imaging, which detects autofluorescent material, i. e., lipofuscin, in the retinal pigment epithelium(RPE). Fluorophores detectable with this imaging method may also occur anterior or posterior to the RPE cell monolayer. Excessive lipofuscin accumulation in the RPE is a common downstream pathogenic pathway in various monogenetic and complex retinal diseases including age-related macular degeneration. The accumulated lipofuscin produces a signal that is captured in the FAF image allowing in vivo mapping of metabolic changes in the RPE.  6, record 1, English, - fundus%20autofluorescence%20imaging

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 OBS

Technique permettant d'obtenir des images qui révèlent une accumulation de lipofuscine sur l'épithélium pigmentaire rétinien.  4, record 1, French, - imagerie%20en%20autofluorescence%20du%20fond%20d%27%26oelig%3Bil

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

Near-infrared reflectance(NIR) imaging is a noninvasive, noncontact, and rapid in vivo examination currently extensively available for ophthalmologists.... the technique enables visualizing subretinal alterations located in the retinal photoreceptor layer, the retinal pigmented epithelium(RPE), and choroid. The basis is a long excitation wavelength([approximately] 820 nm [nanometres] diode laser) that penetrates the optic media and enables visualizing the retina and choroid in detail. Changes in reflection and absorption of light through retinal tissues enhance visualization of structures beneath the retinal pigment epithelium(RPE) and melanin. Images often correlate with blue-light fundus autofluorescence(FAF) ;however, NIR demonstrates superiority in revealing sub-RPE lesions.  2, record 2, English, - near%2Dinfrared%20reflectance%20imaging

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

L'imagerie par réflectance en proche infrarouge [...] utilise des rayons de longueur d'onde élevée, de l'ordre de 804-805 nm [nanomètres], pour donner une image du fond d'œil. Cela fait que les rayons pénètrent profondément dans les structures oculaires et permettent une bonne visualisation de la rétine externe, de l'épithélium pigmentaire (EP) et de la choroïde.  1, record 2, French, - imagerie%20par%20r%C3%A9flectance%20en%20proche%20infrarouge

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

Autosomal recessive bestrophinopathy.... Biaellic mutations in BEST1 are associated with a distinct retinopathy characterized by central visual loss, an absent EOG [electrooculogram] light-rise, and a reduced EOG. Yellowish blunt retinal deposits may be confused with an inflammatory uveitis-like condition, but FAF [fundus autofluorescence] reveals them to be hyperfluorescent.  3, record 3, English, - autosomal%20recessive%20bestrophinopathy

Record number: 3, Textual support number: 2 CONT

Autosomal recessive bestrophinopathy (ARB). Typical age of onset in ARB is in the first decade but can be as late as the fifth decade.  4, record 3, English, - autosomal%20recessive%20bestrophinopathy

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 CONT

Bestrophinopathie autosomique récessive. [...] une [...] entité associée à des mutations autosomiques récessives sur le gène BEST1 a été décrite sous le nom de bestrophinopathie autosomique récessive [...] L'âge de début est variable mais typiquement dans l'enfance. [...] L'examen du fond d'œil met en évidence de grossières taches jaunâtres au pôle postérieur avec des remaniements maculaires kystiques. Les dépôts jaunâtres sont mieux lisibles par imagerie en autofluorescence, laquelle souligne aussi l'aspect stellaire des remaniements maculaires kystiques.  1, record 3, French, - bestrophinopathie%20autosomique%20r%C3%A9cessive

Record 3,  Textual support,  Spanish