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GABA [7 records]
Record 1 - internal organization data 2025-05-27
Record 1, English
Record 1, Subject field(s)
- Medication
Record 1, Main entry term, English
- benzodiazepine
1, record 1, English, benzodiazepine
correct, noun
Record 1, Abbreviations, English
- BZD 2, record 1, English, BZD
correct, noun
Record 1, Synonyms, English
- benzo 3, record 1, English, benzo
correct, noun, familiar
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Any of a group of compounds having a common molecular structure and acting similarly as depressants in the central nervous system, their actions including antianxiety, sedative, hypnotic, amnestic, anticonvulsant, and muscle relaxing effects. 4, record 1, English, - benzodiazepine
Record number: 1, Textual support number: 1 CONT
Benzodiazepines(BZD) are drugs marketed since the 1960s that act on the central nervous system through GABA [gamma-aminobutyric acid] receptors. 5, record 1, English, - benzodiazepine
Record 1, French
Record 1, Domaine(s)
- Médicaments
Record 1, Main entry term, French
- benzodiazépine
1, record 1, French, benzodiaz%C3%A9pine
correct, feminine noun
Record 1, Abbreviations, French
- BZD 2, record 1, French, BZD
correct, feminine noun
Record 1, Synonyms, French
- benzo 3, record 1, French, benzo
correct, feminine noun, familiar
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les benzodiazépines agissent, au niveau du système nerveux central, sur des récepteurs spécifiques étroitement liés aux récepteurs du GABA (acide gamma-aminobutyrique) et au canal du chlore. 4, record 1, French, - benzodiaz%C3%A9pine
Record number: 1, Textual support number: 1 OBS
[...] les réponses de l'organisme aux benzodiazépines correspondent à une diminution de l'activité neuronale : diminution de l'anxiété (effet anxiolytique), diminution de la vigilance (effet sédatif et hypnotique), diminution d'origine centrale du tonus musculaire (effet myorelaxant, anticonvulsivant et antiépileptogène). Chaque benzodiazépine induit l'ensemble de ces réponses, mais l'une ou l'autre peut être plus marquée. 5, record 1, French, - benzodiaz%C3%A9pine
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Medicamentos
Record 1, Main entry term, Spanish
- benzodiacepina
1, record 1, Spanish, benzodiacepina
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
Las benzodiacepinas pertenecen al grupo de medicamentos llamados depresores del sistema nervioso central, (medicamentos que frenan el sistema nervioso). [...] Muchas de las benzodiacepinas se utilizan en el tratamiento de otras condiciones, también. Diazepam se utiliza para ayudar a relajar los músculos o aliviar los espasmos musculares. 2, record 1, Spanish, - benzodiacepina
Record 1, Key term(s)
- benzodiazepina
Record 2 - internal organization data 2022-10-11
Record 2, English
Record 2, Subject field(s)
- Medication
- Nervous System
- Biochemistry
Record 2, Main entry term, English
- psychotropic drug
1, record 2, English, psychotropic%20drug
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- psychotropic medication 2, record 2, English, psychotropic%20medication
correct
- psychotropic 3, record 2, English, psychotropic
correct, noun
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
There are five main types of psychotropic medications: antidepressants, anti-anxiety medications, stimulants, antipsychotics, and mood stabilizers. 4, record 2, English, - psychotropic%20drug
Record number: 2, Textual support number: 2 CONT
Psychotropics are a broad category of drugs that treat many different conditions. They work by adjusting levels of brain chemicals, or neurotransmitters, like dopamine, gamma aminobutyric acid(GABA), norepinephrine, and serotonin. 3, record 2, English, - psychotropic%20drug
Record 2, French
Record 2, Domaine(s)
- Médicaments
- Système nerveux
- Biochimie
Record 2, Main entry term, French
- médicament psychotrope
1, record 2, French, m%C3%A9dicament%20psychotrope
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- psychotrope 1, record 2, French, psychotrope
correct, masculine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Les médicaments psychotropes agissent sur le système nerveux central, en modifiant certains processus biochimiques et physiologiques du cerveau. Les cellules nerveuses (neurones) synthétisent des substances appelées neuromédiateurs (ou neurotransmetteurs), principalement : la dopamine, la sérotonine et la noradrénaline. Ces neuromédiateurs interviennent dans le fonctionnement des neurones. On observe une perturbation de ces neuromédiateurs dans certains troubles, comme les troubles dépressifs, les troubles bipolaires, les troubles anxieux ou les troubles schizophréniques. Les médicaments psychotropes agissent sur ces neuromédiateurs. Ils ont aussi des effets autres que psychiques, ce qui explique d'ailleurs certains de leurs effets indésirables. Ils sont habituellement classés en cinq grands groupes : 1. antidépresseurs, 2. neuroleptiques (dits aussi antipsychotiques), 3. anxiolytiques (tranquillisants), 4. hypnotiques (somnifères), 5. stabilisants de l'humeur (dits aussi régulateurs de l'humeur, thymorégulateurs, ou parfois normothymiques). 2, record 2, French, - m%C3%A9dicament%20psychotrope
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Medicamentos
- Sistema nervioso
- Bioquímica
Record 2, Main entry term, Spanish
- psicofármaco
1, record 2, Spanish, psicof%C3%A1rmaco
correct, masculine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
- psicotrópico 2, record 2, Spanish, psicotr%C3%B3pico
avoid, see observation, masculine noun
- sicotrópico 2, record 2, Spanish, sicotr%C3%B3pico
avoid, see observation, masculine noun
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 DEF
Fármaco de la familia de los ansiolíticos, hipnóticos, antidepresivos, antipsicóticos o antiepilépticos. 1, record 2, Spanish, - psicof%C3%A1rmaco
Record number: 2, Textual support number: 1 OBS
psicotrópico; sicotrópico: Debería reservarse su uso a la forma adjetival. 3, record 2, Spanish, - psicof%C3%A1rmaco
Record 3 - internal organization data 2015-06-02
Record 3, English
Record 3, Subject field(s)
- Biological Sciences
Record 3, Main entry term, English
- glutamate decarboxylase
1, record 3, English, glutamate%20decarboxylase
correct
Record 3, Abbreviations, English
- GAD 1, record 3, English, GAD
correct
Record 3, Synonyms, English
- glutamic acid decarboxylase 1, record 3, English, glutamic%20acid%20decarboxylase
correct
- GAD 1, record 3, English, GAD
correct
- GAD 1, record 3, English, GAD
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
The essential enzyme that catalyzes the conversion of glutamate to the neurotransmitter GABA [gamma-amino butyric acid]. 1, record 3, English, - glutamate%20decarboxylase
Record 3, French
Record 3, Domaine(s)
- Sciences biologiques
Record 3, Main entry term, French
- glutamate décarboxylase
1, record 3, French, glutamate%20d%C3%A9carboxylase
correct, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
- acide glutamique décarboxylase 2, record 3, French, acide%20glutamique%20d%C3%A9carboxylase
correct, masculine noun
Record 3, Textual support, French
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2015-02-23
Record 4, English
Record 4, Subject field(s)
- Nervous System
Record 4, Main entry term, English
- thalamic reticular nucleus
1, record 4, English, thalamic%20reticular%20nucleus
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
- reticular nucleus 1, record 4, English, reticular%20nucleus
correct
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
... they make cholinergic connections not only in its sensory areas, but also in its reticular nucleus, a layer of neurons that surrounds the thalamus like a skin and exerts a general inhibiting effect on it by means of the neurotransmitter GABA [gamma-aminobutyric acid]. 1, record 4, English, - thalamic%20reticular%20nucleus
Record 4, French
Record 4, Domaine(s)
- Système nerveux
Record 4, Main entry term, French
- noyau réticulaire thalamique
1, record 4, French, noyau%20r%C3%A9ticulaire%20thalamique
correct, masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
- noyau réticulaire 1, record 4, French, noyau%20r%C3%A9ticulaire
correct, masculine noun
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Le noyau réticulaire thalamique. Ce noyau en forme de croissant borde la partie externe du thalamus. Il contient de grandes cellules fusiformes qui sont toutes GABAergiques et qui exercent une action inhibitrice sur les cellules de relais. Le noyau réticulaire comprend des secteurs visuel, auditif, somesthésique, etc., qui sont en relation synaptique avec les noyaux thalamiques correspondant à ces modalités sensorielles. 1, record 4, French, - noyau%20r%C3%A9ticulaire%20thalamique
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2013-10-10
Record 5, English
Record 5, Subject field(s)
- Nervous System
Record 5, Main entry term, English
- gamma-aminobutyric acid receptor
1, record 5, English, gamma%2Daminobutyric%20acid%20receptor
correct, see observation
Record 5, Abbreviations, English
Record 5, Synonyms, English
- GABA receptor 2, record 5, English, GABA%20receptor
correct
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
GABA(gamma-aminobutyric acid) receptors are divided into three classes : A, B and C. The GABA-A receptor is very complex, composed of five subunits, and containing a chloride channel, estimated to be about 5 nm in diameter. 2, record 5, English, - gamma%2Daminobutyric%20acid%20receptor
Record number: 5, Textual support number: 1 OBS
gamma: This word must be italicized or replaced by the corresponding Greek letter. 3, record 5, English, - gamma%2Daminobutyric%20acid%20receptor
Record 5, Key term(s)
- γ-aminobutyric acid receptor
Record 5, French
Record 5, Domaine(s)
- Système nerveux
Record 5, Main entry term, French
- récepteur de l'acide gamma-aminobutyrique
1, record 5, French, r%C3%A9cepteur%20de%20l%27acide%20gamma%2Daminobutyrique
correct, see observation, masculine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
- récepteur de GABA 2, record 5, French, r%C3%A9cepteur%20de%20GABA
correct, masculine noun
Record 5, Textual support, French
Record number: 5, Textual support number: 1 CONT
Le traducteur final des états d'anxiété, d'angoisse et de dépression est certainement le complexe amygdalien. Cette structure est particulièrement riche en récepteurs de l'acide gamma-aminobutyrique (GABA), le neurotransmetteur chargé de l'inhibition de pratiquement tout le cerveau. 2, record 5, French, - r%C3%A9cepteur%20de%20l%27acide%20gamma%2Daminobutyrique
Record number: 5, Textual support number: 1 OBS
gamma : Ce mot s'écrit en italique ou doit être remplacé par la lettre grecque correspondante. 3, record 5, French, - r%C3%A9cepteur%20de%20l%27acide%20gamma%2Daminobutyrique
Record 5, Key term(s)
- récepteur de l'acide γ-aminobutyrique
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 1998-02-12
Record 6, English
Record 6, Subject field(s)
- Biochemistry
Record 6, Main entry term, English
- neurosteroid
1, record 6, English, neurosteroid
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 CONT
Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus (Proc. Natl. Acad. Sci. USA, December 23, 1997). 2, record 6, English, - neurosteroid
Record number: 6, Textual support number: 1 OBS
Neurosteroids potentiate the gamma aminobutyric acid(GABA) response in all possible forms of the GABA receptor. 3, record 6, English, - neurosteroid
Record 6, Key term(s)
- Preg S
Record 6, French
Record 6, Domaine(s)
- Biochimie
Record 6, Main entry term, French
- neurostéroïde
1, record 6, French, neurost%C3%A9ro%C3%AFde
correct, masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 CONT
Le taux du neurostéroïde sulfate de prégnenolone (PregS) dans l'hippocampe est plus bas chez les rats âgés que chez les adultes. 1, record 6, French, - neurost%C3%A9ro%C3%AFde
Record 6, Key term(s)
- Preg S
- sulfate de pregnenolone
Record 6, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 1997-11-06
Record 7, English
Record 7, Subject field(s)
- Biochemistry
Record 7, Main entry term, English
- endozepine
1, record 7, English, endozepine
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 CONT
Human endozepine, an 86 amino acid polypeptide, was originally isolated from human brain tissue as a putative ligand of the benzodiazepine receptor. Complete amino acid sequencing of the human and bovine proteins revealed significant homology with the partial sequence of diazepam binding inhibitor(DBI), a protein from rat brain. Both endozepine and DBI have been shown to elicit behavioral effects, suggesting that they function as pharmacologically-active ligands of the GABA. 2, record 7, English, - endozepine
Record 7, French
Record 7, Domaine(s)
- Biochimie
Record 7, Main entry term, French
- endozépine
1, record 7, French, endoz%C3%A9pine
correct, feminine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 CONT
Compte tenu de la présence potentielle du (DBI) [diazapam-binding inhibitor] et des peptides qui lui sont apparentés (habituellement désignés sous le nom d'endozépines), on s'attendait à ce que ces peptides suscitent un grand nombre d'études neurochimiques et comportementales, à l'instar des ligands endogènes des récepteurs des opiacés. 1, record 7, French, - endoz%C3%A9pine
Record 7, Spanish
Record 7, Textual support, Spanish
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