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GENE RADIATION [2 records]

Record 1 2012-09-04

English

Subject field(s)
  • Genetics
CONT

Positional cloning of disease gene loci assigned to 8q24 can be assisted by a high resolution map of this genomic area. In an effort to improve the resolution of the 8q24 map, we have undertaken radiation hybrid(RH) mapping. This method compliments the existing mapping strategies of meiotic mapping(Gyapay et al., 1994) and somatic cell hybrid panels(Wagner et al., 1991; Parrish et al., 1994), but at a higher resolution and with particular emphasis on defining the order and intermarker distance of loci in regions of interest.

French

Domaine(s)
  • Génétique
DEF

Clonage d'un gène inconnu par des procédés de cartographie génétique, puis physique.

Spanish

Campo(s) temático(s)
  • Genética
DEF

Estrategia de clonación de genes basada en la identificación de marcadores estrechamente ligados al carácter diana, y que utiliza el paseo cromosómico para identificar, aislar y caracterizar el gen o los genes responsables del carácter.

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Record 2 2004-01-27

English

Subject field(s)
  • Spacecraft
  • Research Experiments in Space
CONT

The Insect Habitat(IH) was designed to support a variety of insect species. However, during the initial flight increments, it will be dedicated to experiments using Drosophila melanogaster, or fruit flies. The Insect Habitat will enable studies of the fruit fly to learn how microgravity affects development, nervous system function, movement and behavior, growth, reproduction, aging, gene expression, mutagenesis from radiation and circadian rhythms or sleep/wake cycles.

CONT

The IH will support single- and multi-generation experiments that have approximate external dimensions of 13.5 cm (L) x 2.25 cm (D) x 7.0 cm (H) each. The flies will live in two chevron-shaped container elements. These containers can be divided into two parts using the internal food cylinders; this yields two 55 ml containers that can support up to 100 Drosophila through to egg-laying. Alternatively, the containers can be left undivided, which yields a single 110 ml volume that supports up to 200 Drosophila. ... The two insect containers reside in the science element portion of the IH. The science element consists of two environmentally controlled "drawers." Each drawer contains a centrifuge that can provide up to 2G. Each centrifuge will hold six insect containers. Typically, one drawer will have a microgravity environment and the other drawer will have a defined gravity environment, although the precise gravity regimen for each centrifuge can be determined by the researcher.

CONT

Insect Habitat (IH) for Space Station - The Insect Habitat System consists of a Transport Element, Science Element and an Insect Container Element.

OBS

Habitats in the Space Station Fundamental Biology Research Facility (SSFBRF) enable studies on a variety of organisms across multiple science disciplines. They allow scientists to conduct experiments in habitats that are similar in design to those that have been used in labs for ground studies. Each habitat provides life support, environmental control, and monitoring systems and can be housed in one or more of the three major host systems: the Centrifuge, Life Sciences Glovebox, and Habitat Holding Rack. This hardware was designed to automate as much as possible, thus providing maximizing science return while requiring minimal crew time.

OBS

insect habitat; IH: term and abbreviation officially approved by the International Space Station official approval Group (ISSOAG).

French

Domaine(s)
  • Engins spatiaux
  • Travaux de recherche dans l'espace
CONT

[...] le Compartiment canadien pour insectes devant être lancé à destination de l'ISS en 2004.

CONT

Le laboratoire pour insectes (Insect Habitat Facility) subira quant à lui des essais rigoureux ici sur Terre en vue de son lancement à bord de l'ISS [International Space Station] au milieu de 2005.

OBS

compartiment canadien pour insectes; IH : terme et abréviation uniformisés par le Groupe de travail de la terminologie de la Station spatiale internationale (GTTSSI).

Spanish

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