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GENE SILENCING [5 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2013-09-19

English

Subject field(s)
  • Genetics
CONT

Silent genes and everlasting fruits and vegetables?... An intriguing feature of gene silencing is that partial or almost complete gene inactivation can be obtained, depending on the position(and perhaps the structure and copy number) of the transgene. For both sense and antisense gene silencing, transformants can be selected where genetic change is stably inherited.

French

Domaine(s)
  • Génétique
OBS

silençage : Région de l'ADN qui diminue la transcription d'un gène voisin de cette région.

OBS

silenceur : La méthylation de l'ADN et le développement des végétaux, paramutations et interactions alléliques, les mécanismes de silençage de l'expression génétique.

Spanish

Campo(s) temático(s)
  • Genética
DEF

Pérdida de expresión génica por una alteración en la secuencia de ADN de un gen estructural o de su región reguladora o bien por las interacciones entre su transcrito y otros ARNm [ácido ribonucleico mensajero] que se encuentran en la célula.

CONT

Silenciamiento génico. Gen que no se expresa debido a la regulación epigenética. A diferencia de los genes que son mutantes debido a alteraciones en su secuencia de DNA, los genes inactivados mediante silenciamiento pueden volver a ser activados.

Save record 1

Record 2 2011-08-31

English

Subject field(s)
  • Genetics
  • Biotechnology
CONT

Using this knowledge, an emerging use of PTGS and, in particular, RNA interference (RNAi), the initiating of PTGS by introducing small (21-25 nucleotides) double-stranded RNA (siRNA), as a tool to knock out the expression of specific genes in a variety of organisms can be observed.

OBS

Epigenic silencing of transgene and endogenous genes can occur at the transcriptional level (TGS) or at the post-transcriptional level (PTGS).

OBS

post-transcriptional silencing : Elliptical form of "post-transcriptional gene silencing. "As the term "silencing" can only apply in this context to genes, the term "gene" can be removed.

Key term(s)
  • posttranscriptional gene silencing

French

Domaine(s)
  • Génétique
  • Biotechnologie
DEF

Phénomène ou mécanisme cytoplasmique de mise en sommeil des gènes qui peut être d'origine naturelle ou provoqué in vitro et qui induit une destruction sélective de l'ARNm [ARN messager] pour lequel correspondent au moins une centaine de nucléotides.

OBS

PTGS : Bien qu'issue de l'expression anglaise «Post Transcriptional Gene Silencing», cette abréviation est utilisée dans les textes français.

Spanish

Campo(s) temático(s)
  • Genética
  • Biotecnología
DEF

Degradación citoplasmática del ARNm [ácido ribonucleico mensajero] de un gen específico debido a la presencia de ARNbc [ácido ribonucleico bicatenario] complementarios a él.

Save record 2

Record 3 2011-05-09

English

Subject field(s)
  • Genetics
  • Biotechnology
CONT

RNA interference(RNAi) is an evolutionarily conserved mechanism in plant and animal cells that directs the degradation of messenger RNAs homologous to short double-stranded RNAs termed "small interfering RNA"(siRNA). The ability of siRNA to direct gene silencing in mammalian cells has raised the possibility that siRNA might be used to investigate gene function in a high throughput fashion or to modulate gene expression in human diseases.

French

Domaine(s)
  • Génétique
  • Biotechnologie
DEF

Petit fragment d'ARN double brin d'une longueur de 21 à 25 nucléotides qui peut inhiber l'expression d'un gène.

OBS

Les petits ARN interférents se distinguent des micro-ARN (miARN) par leur origine et la diversité des fonctions auxquelles ils sont associés. À l'inverse des miARN, les petits ARN interférents ne sont produits pas des gènes, mais ils résultent de la fragmentation d'ARN double-brin par le mécanisme d'interférence à l'ARN.

Spanish

Save record 3

Record 4 2005-02-08

English

Subject field(s)
  • Biochemistry
CONT

We hope to elucidate the role of adenosine kinase(ADK) and that of the adenine salvage pathway in plant systems by isolating and characterizing ADK-deficient mutants from Arabidopsis thaliana. To achieve this goal, both a direct selection, previously employed for mammalian systems, and gene silencing are being used.

French

Domaine(s)
  • Biochimie
Key term(s)
  • adénosine-kinase

Spanish

Save record 4

Record 5 1997-01-20

English

Subject field(s)
  • Genetics
CONT

Silent genes and everlasting fruits and vegetables?... An intriguing feature of gene silencing is that partial or almost complete gene inactivation can be obtained, depending on the position(and perhaps the structure and copy number) of the transgene. For both sense and antisense gene silencing, transformants can be selected where genetic change is stably inherited.

French

Domaine(s)
  • Génétique

Spanish

Save record 5

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