TERMIUM Plus®
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GENE SUBSTITUTION [4 records]
Record 1 - internal organization data 1997-06-18
Record 1, English
Record 1, Subject field(s)
- Microbiology and Parasitology
Record 1, Main entry term, English
- reassortant vaccine
1, record 1, English, reassortant%20vaccine
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
A variety of approaches is being used to develop a vaccine. The most advanced are live oral vaccines developed by scientists at the US National Institutes of Health and Wistar Institute, in collaboration with US vaccine manufacturers. These are "re-assortant" vaccines-so-called because they are based on an animal strain of rotavirus(from a monkey or cow) that has been modified by the substitution of gene segments from human strains of the virus. These genes encode protective antigens from the outer shell of the virus. The vaccines include genes from the four serotypes of rotavirus most commonly found-all of which occur in children. They are produced in tissue culture. 1, record 1, English, - reassortant%20vaccine
Record 1, French
Record 1, Domaine(s)
- Microbiologie et parasitologie
Record 1, Main entry term, French
- vaccin réassorti
1, record 1, French, vaccin%20r%C3%A9assorti
proposal, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
réassortir : Reconstituer un assortiment en complétant ou en remplaçant ce qui manque. 2, record 1, French, - vaccin%20r%C3%A9assorti
Record number: 1, Textual support number: 2 OBS
Proposition approuvée par un chercheur de l'Unité de vaccinologie du Centre hospitalier de l'Université Laval (CHUL) à Québec. 1, record 1, French, - vaccin%20r%C3%A9assorti
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 1992-01-27
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- gene substitution
1, record 2, English, gene%20substitution
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 OBS
(...), the distinction between gene mutation in the individual and gene substitution in the population should be kept in mind; only the latter is directly related to molecular evolution. 2, record 2, English, - gene%20substitution
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- substitution de gènes
1, record 2, French, substitution%20de%20g%C3%A8nes
feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- substitution allélique 2, record 2, French, substitution%20all%C3%A9lique
feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 OBS
(...), il faut toujours garder à l'esprit la distinction entre mutation génique chez l'individu et substitution allélique dans la population: seule cette dernière concerne directement l'évolution moléculaire. 2, record 2, French, - substitution%20de%20g%C3%A8nes
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 1980-09-01
Record 3, English
Record 3, Subject field(s)
- Microbiology and Parasitology
Record 3, Main entry term, English
- beta chain 1, record 3, English, beta%20chain
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 OBS
The alpha and beta chains have essentially the same structure, are about the same length and show roughly the same rate of evolutionary amino acid substitution. They arose through gene duplication some 450 million years ago and became differentiated as they accumulated mutations independently. 1, record 3, English, - beta%20chain
Record 3, French
Record 3, Domaine(s)
- Microbiologie et parasitologie
Record 3, Main entry term, French
- chaîne bêta 1, record 3, French, cha%C3%AEne%20b%C3%AAta
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 OBS
Les chaînes alpha et bêta ont approximativement la même structure, sont de longueur à peu près identique et présentent des taux de substitution d'acide aminé voisins. Elles se sont formées, il y a quelque 450 millions d'années, par duplication génique, puis se sont différenciées indépendamment par accumulation de mutations. 1, record 3, French, - cha%C3%AEne%20b%C3%AAta
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 1980-09-01
Record 4, English
Record 4, Subject field(s)
- Microbiology and Parasitology
Record 4, Main entry term, English
- alpha chain 1, record 4, English, alpha%20chain
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 OBS
The alpha and beta chains have essentially the same structure, are about the same length and show roughly the same rate of evolutionary amino acid substitution. They arose through gene duplication some 450 million years ago and became differentiated as they accumulated mutations independently. 1, record 4, English, - alpha%20chain
Record 4, French
Record 4, Domaine(s)
- Microbiologie et parasitologie
Record 4, Main entry term, French
- chaîne alpha 1, record 4, French, cha%C3%AEne%20alpha
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 OBS
Les chaînes alpha et bêta ont approximativement la même structure, sont de longueur à peu près identique et présentent des taux de substitution d'acide aminé voisins. Elles se sont formées, il y a quelque 450 millions d'années, par duplication génique, puis se sont différenciées indépendamment par accumulation de mutations. 1, record 4, French, - cha%C3%AEne%20alpha
Record 4, Spanish
Record 4, Textual support, Spanish
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