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GLQ-223 [1 record]
Record 1 - internal organization data 2005-05-05
Record 1, English
Record 1, Subject field(s)
- Medication
Record 1, Main entry term, English
- Tricosanthin "Q"
1, record 1, English, Tricosanthin%20%5C%22Q%5C%22
correct
Record 1, Abbreviations, English
- GLQ-223 1, record 1, English, GLQ%2D223
correct
Record 1, Synonyms, English
- tricosanthin 2, record 1, English, tricosanthin
correct
- compound Q 2, record 1, English, compound%20Q
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
An artificial form (i.e., produced by recombinant technology) of trichosanthin, a natural substance that shows strong selective activity against HIV-infected cells. 3, record 1, English, - Tricosanthin%20%5C%22Q%5C%22
Record number: 1, Textual support number: 1 OBS
Unlike most other antiviral drugs, which act primarily by preventing new infections in human cells, GLQ-223 selectively kills already HIV-infected macrophages. The specific mechanism by which the drug kills only HIV-infected cells is still under investigation, but tricosanthin is known to inactivate ribosomes in vitro. 2, record 1, English, - Tricosanthin%20%5C%22Q%5C%22
Record 1, Key term(s)
- Tricosanthes kirilowii
Record 1, French
Record 1, Domaine(s)
- Médicaments
Record 1, Main entry term, French
- trichosantine
1, record 1, French, trichosantine
correct, feminine noun
Record 1, Abbreviations, French
- GLQ 223 2, record 1, French, GLQ%20223
correct
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Ainsi, un poison violent, la trichosantine extraite du concombre chinois ou GLQ 223, développée par Genelabs, tue bien des cellules, mais elle s'est avérée également très toxique vis-à-vis des cellules saines de l'organisme. 1, record 1, French, - trichosantine
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Medicamentos
Record 1, Main entry term, Spanish
- compuesto Q
1, record 1, Spanish, compuesto%20Q
masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- tricosantina 1, record 1, Spanish, tricosantina
feminine noun
- GLQ-223 1, record 1, Spanish, GLQ%2D223
correct
Record 1, Textual support, Spanish
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